Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays (Page 117)
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE153806: Differentially expressed genes during pancreatic progenitor cell differentiation and proliferation
A small molecule, AT7867, is a proliferation-promoting factor of human iPS cell-derived pancreatic p...
GSE156057: Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver. [Single cell RNA Seq]
CITE-seq analysis on total CD45+ cells isolated from the livers of mice fed a standard diet (SD) or ...
GSE151519: Heterogenous radiomics patterns are associated with poor survivals and dysregulated pathways in medulloblastoma
Background. To develop a radiomics signature for predicting overall survival (OS) and progression-fr...
GSE142681: Partial loss of CFIm25 causes aberrant alternative polyadenylation and learning deficits [mouse]
We previously showed that NUDT21-spanning copy-number variations (CNVs) are associated with intellec...
GSE146128: Functional Dissection of Transcription Factor Networks Governing Haematopoietic Progenitor States
Blood is generated by a constant stream of differentiating haematopoietic progenitor cells. The proc...
GSE151610: Epithelial membrane protein 2 (EMP2) regulates hypoxia induced angiogenesis in retinal epithelial cells
Pathologic retinal neovascularization is a potentially blinding consequence seen in many common dise...
GSE146754: Smc3 regulates B-cell transit through germinal centers and restricts their malignant transformation (RNA-seq)
During the germinal center (GC) reaction, B-cells undergo extensive redistribution of cohesin comple...
GSE142711: RNA-seq analysis of scramble microPEP(Scr) or microPEP155(P155) treated THP1-derived dendritic cells
The goals of this study are to compare the clusters and pathways of differential genes in scramble m...
GSE144461: Stress-induced beta cell dedifferentiation prior to immune cell infiltration prevents type 1 diabetes [Bulk]
Immune-mediateddestruction of insulin-producing -cells causes type 1 diabetes (T1D). However, how-ce...
GSE144796: Gene expression changes in cardiomyocytes from normal mice and diabetic, high fat diet-fed mice exposed to the DPP-4 inhibitor linagliptin
Cardiomyocytes were isolated from the hearts of C57BL/6 mice or C57BL/6 mice that had been fed a hig...
GSE151514: Identification of 17-DMAG as a novel KDM4B inhibitor for combination therapy [RNA-seq]
Histone lysine demethylases (KDMs) are emerging as therapeutic targets in cancer. Development of pot...
GSE144421: Tissue-specific factors differentially regulate the expression of antigen-processing enzymes during dendritic cell ontogeny
Dendritic cells (DC) form a collection of antigen-presenting cells that are distributed throughout t...
GSE144726: Prominin-1-expressing Hepatic Progenitor Cells Induce Fibrogenesis in Murine Cholestatic Liver Injury
Purpose: Cholestatic liver injury is associated with intrahepatic biliary fibrosis, which can progre...
GSE146742: Examination of gene expression in different populations of the embryonic thymus at E15.5 and E19.5 by bulk RNA-seq
ILC2 contribute to immune homeostasis, protective immunity and tissue repair. However, an understan...
GSE154369: Involvement of circulating factors in the transmission of paternal experiences through the germline
Using a mouse model of paternal exposure to traumatic stress, we identify circulating factors involv...
GSE155918: Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity
We report the whole genome transcriptomic responses of ape species (human, common chimpanzee) and AA...
GSE151791: RNA-seq muscle
Identify the genes modulated by Glucocorticoid Receptor. SOURCE: Delphine Duteil (delphine.duteil@ig...
GSE151912: Wide-spread disruption of transcription termination in HSV-1 infection: Next generation sequencing of total and newly transcribed (4sU-RNA) RNA from different virus strains and mutant viruses
Primary human foreskin fibroblasts (HFF) were infected with the indicated HSV-1 strains and mutants ...
GSE65926 (human): Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed
Circular RNAs (circRNAs) are an endogenous class of animal RNAs. Despite their abundance, their func...
GSE149824: Therapeutic decoupling of MHC-I and PD-L1 expression increases the efficacy of immune checkpoint blockade (koTRAF3_RNAseq)
Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of multiple cancers, but t...
GSE147263: RNA-Seq of CD8+ T cell subsets in B16-GP33 tumor
Tissue-resident memory CD8+ T cells (Trm) provide host protection through continuous surveillance of...
GSE153685: Bulk RNA-Sequencing of Murine Normal and Tumor-Associated Omental and Mesenteric Macrophages
The omentum is the most common site of ovarian cancer metastasis. Immune cell clusters called milky ...
GSE156285: Single cell RNA sequencing analyses of cells from human sinonasal tissue
Single cell RNA sequencing analyses of human sinonasal tissue samples of chronic rhinosinusitus pati...
GSE146865: Saracatinib drug treatment of mouse primary microglia cultures
To test the effect of saracatinib on gene expression patterns in microglia, we treated mouse (C57BL/...
GSE150768: The environment-sensing aryl-hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions
Aryl-hydrocarbon receptor protects against endochondral ossification of modulated smooth muscle cell...
GSE156449: Nociceptive nerves regulate haematopoietic stem cell mobilization
Nociceptive neuropeptide CGRP acts directly on HSCs via the its receptor RAMP1/CALCRL, to promote eg...
GSE146796: Next-generation sequencing reveals size-dependent pulmonary impact of thin graphene oxide sheets in mice: towards safe-by-design
Safety assessment of graphene-based materials (GBMs) including graphene oxide (GO) is essential for ...
GSE156060: Influenza non-structural protein 1 (NS1) localization plays a key role in the anatagonism of host antiviral processes.
The influenza virus is opportunistic by nature and is capable of subverting cellular signalling path...
GSE154386: Temporally integrated single cell RNA sequencing analysis of controlled and natural DENV-1 infections
Controlled dengue human challenge studies present a unique opportunity to address many longstanding ...
GSE154069: The Role of Satb1 in Shaping the Repertoire of T Cell Receptor Genes
To explore the role of Satb1 in rearrangement and repertoire of TCR genes, we used Satb1contional kn...
GSE144787: TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T cell numbers
Host immune response is a fundamental mechanism for attenuating cancer progression. Here we report a...
GSE156101: Proteome-wide analysis reveals substrates of E3 ligase RNF146 targeted for degradation
To check whether mRNA level change for the changed proteins in protein level. SOURCE: Litong Nie (LN...
GSE154108: Gcn5 transcriptional activation of Myc-induced genes promotes B-cell lymphomagenesis
Purpose: In this study we sought to elucidate whether Gcn5 cooperates with Myc to induce the formati...
GSE154173: Heat shock protein gp96 induces Foxp3 expression in Regulatory T Cells via interaction with TLRs for treatment of Auto-immune Diseases [FFoxp3-GFP-hCre]
Upregulate and stabilize Foxp3 expression in Treg are essential for manipulating Treg cell function ...
GSE146714: SE-driven metabolic reprogramming in ADPKD (kidney RNA-seq)
Metabolic reprogramming is emerging as a key pathological contributor to the progression of autosoma...
GSE151049: Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin
It is generally believed that bone micro-fractures, associated with osteocyte death, lead to osteocl...
GSE145084: Polyploid hepatocytes are protected from cancer but maintain regenerative capacity in chronic liver disease
BACKGROUND & AIMS: Thirty to ninety percent of hepatocytes contain whole genome duplications, making...
GSE149769: RNAseq analysis of gene expression in colorectal tumors of wild-type and Nlrp12-/- mice
Background: NLRP12 is a cytosolic pattern recognition receptor in the family of NOD-like receptor. N...
GSE156064: Total RNA sequencing of cultured splenic PKM2WT and PKM2KO NK cells
PKM2 has recently been characterised in macrophages and T cells to play a crucial signalling role, i...
GSE154435: Evaluation of Tmem184b dependent gene expression changes during sensory neuron differentiation in vitro
Our objective was to evaluate the gene expression changes occuring in early sensory neuron developme...
GSE153021: Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis
To explore the underlying molecular and cellular mechanisms of increased efficacy of the combination...
GSE145102: Astrocyte Deletion of alpha2-Na/K ATPase Triggers Episodic Motor Paralysis in Mice via a Metabolic Mechanism
Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory...
GSE149815: SHP2 Inhibition Abrogates Adaptive Resistance to KRAS-G12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors
KRAS is the most frequently mutated oncogene in human cancer, and KRAS inhibition has been a longtim...
GSE147961: YAP/TAZ drives ependymoma-like tumour formation in mice
YAP1 gene fusions have been observed in a subset of paediatric ependymomas. Here we show that ectop...
GSE156341: Dynamic changes in RNA-chromatin interactome promote endothelial dysfunction (scRNA-seq human vascular)
Chromatin-associated RNA has been proposed as a type of epigenomic modification. Here, we test wheth...
GSE154032: HIF1 is an essential regulator of steroidogenesis in the adrenal gland
Hormones produced by the adrenal cortex are absolutely essential for numerous processes in living an...
GSE156052: Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver. [Bulk RNA Seq]
CITE-seq analysis on total CD45+ cells isolated from the livers of mice fed a standard diet (SD) or ...
GSE156805: Mitochondrial Potentiation Ameliorates Age Related Heterogeneity in Hematopoietic Stem Cell Function [MMPhigh and MMPlow HSCs]
introduction: Ageing is associated with reduced fitness and increased myeloid bias of the hematopoie...
GSE156988: FD-seq: Droplet-based RNA sequencing of fixed single cells
Current high-throughput single-cell RNA sequencing (scRNA-seq) methods are incompatible with parafor...
GSE154450: RNAseq analysis of EC109 cells transfected by lncRPL34-AS1 plasmid and scramble pcDNA
We constructed EC109 cells transfected by lncRPL34-AS1 plasmid and scramble pcDNA to select differen...
GSE156856: Coagulopathy in Malnourished Mice is Sexually Dimorphic and Regulated by Nutrient-sensing Nuclear Receptors
Liver dysfunction including coagulopathy is a prominent feature of proteinenergy malnutrition. To id...
GSE153812: The serotonin transporter is a regulator of neurodegeneration and axon regeneration after retinal injury
Loss of specialized neurons in neurodegenerative diseases and after nerve injury is mediated in a ne...
GSE48889: SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample
mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are inc...
GSE49682: Primate transcript and protein expression levels evolve under compensatory selection pressures
Variation in gene regulation is thought to have played an important role in the evolution of primate...
GSE149832: Expression profile of circRNA and mRNA in lacrimal glands of AQP5-/- mice with primary dry eye
Purpose: Identify the differentially expressedcircular RNA (circRNA) and elucidate their potential f...
GSE147182: Dynamic Regulation of Tfh Clonal Selection During the Germinal Center Reaction
The Germinal center is a dynamic microenvironment wherein B cells expressing high affinity antibody ...
GSE156335: Protein stability buffers the cost of translation attenuation following eIF2 phosphorylation
Quantification of total and polysome-associated RNAs from mouse liver following tunicamycin (Tm) tre...
GSE53066: Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq.
We generated A673 Ewing Sarcoma cell lines which stably express shRNA targeting the EWS-FLI1 fuison ...
GSE51005: Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy
Early chemotherapy for advanced/metastatic non-castration resistant prostate cancer (PCa) may improv...
GSE154181: Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntingtons disease mutations
Huntingtons disease (HD) is a dominantly inherited neurodegenerative disorder caused by a trinucleot...
GSE146861: Dppa2/4 Counteract De Novo Methylation to Establish a Permissive Epigenome for Development [RNA-seq]
Early mammalian development entails widespread epigenome remodeling, including DNA methylation erasu...
GSE146336: Thyroid hormone receptor a in skeletal muscle is essential for thyroid thermogenesis
Thyroid hormones are important for homeostatic control of energy metabolism and body temperature. Al...
GSE156118: RNA-sequencing of QKI proficient and deficient microglia
Purpose:RNA_sequencing analysis defined a novel role for the QKI in microglia; Methods: microglia m...
GSE145445: Effects of COP1 deletion in microglia in vivo
The realization in the last decade that dysregulated microglia are intimately involved in Alzheimers...
GSE153727: Transcriptomes of human neutrophils before and after in vivo exposure to Bacillus Calmette-Gurin vaccine
Innate immune memory is the phenomenon whereby innate immune cells undergo functional reprogramming ...
GSE157109: Gene expression profiling data following TRIM8 knockdown in MCF-7 cells
Breast cancer (BC) is the most common female malignancies worldwide, and 70% of cases are estrogen r...
GSE154442: RNA-Seq of enriched astrocytes with MADM induced UPD of Chr. 7 (SMARTer)
In mammalian genomes a subset of genes is regulated by genomic imprinting resulting in silencing of ...
GSE145169: The human gene FOXM1 promotes cortical folding and improves learning and memory ability in mice
Purpose: To gain futher insight into how FOXM1 regulates the proliferative of neural progenitors ,RN...
GSE149934: Functional genomic landscape of cancer-intrinsic immune evasion to cytotoxic T lymphocyte killing [RNA-seq I]
The genetic circuits that allow cancer cells to evade destruction by the host immune system remain p...
GSE147298: BMP signaling: at the gate between activated melanocyte stem cells and differentiation [SMART-Seq2 single cell RNA-seq]
Adult tissue stem cells protect their long-term potential by exerting precise control over their tra...
GSE149880: Expression analysis of WT or Card14E138A ears 5 days and 1 month after injecton of tamoxifen
The inducible nature of our knock-in mouse strain allowed us to determine the immediate effects of d...
GSE146332: Next Generation Sequencing Facilitates Quantitative Analysis of Runx2fl/fl and Gli1-CreERT2;Runx2fl/fl Incisor Transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE156034: RNA sequencing analysis of OTUD6B-knockdown KYSE30 cells
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE157121: Transcriptional response of thyroid to iodide in wild-type and Nrf2 knockout mice
Analysis of differentially expressed mRNAs indicated that iodide overload upregulated inflammatory-,...
GSE153824: Complementary networks of cortical somatostatin interneurons enforce layer specific control
The neocortex is functionally organized into layers. Layer four receives the densest bottom up senso...
GSE145243: Erythrophagocytosis drives anti-inflammatory programming of liver macrophages (Bulk RNA seq BMDMs)
Under conditions of erythrolytic stress, which accompanies many disease states, macrophages play key...
GSE156089: Analysis of transcriptome changes of human epidermal stem cells treated by EGF
We report the application of transcriptome sequencing technology in the analysis of transcriptome ch...
GSE157144: Mechanisms of interleukin 4 mediated increase in efficacy of vaccines against opioid use disorders.
We report our results of RNA-sequencing analysis of mouse lymph nodes and spleens after administrati...
GSE53638: Characterization of differentiating adipose cells by high-throughput single-cell RNA-Seq
Directed differentiation of cells in vitro is a powerful approach for dissection of developmental pa...
GSE154188: Chromatin topology and the timing of enhancer function at the HoxD locus [RNA-seq]
The HoxD gene cluster is critical for proper limb formation in tetrapods. In the emerging limb buds,...
GSE148973: An Integrated Epigenomic and Transcriptomic Map of Mouse and Human ab T Cell Development (RNAseq EXP1)
ab lineage T cells, most of which are CD4+ or CD8+ and recognize MHC I or MHC II-presented antigens,...
GSE145242: Erythrophagocytosis drives anti-inflammatory programming of liver macrophages (Bulk RNA seq SPTA CD40 mac)
Under conditions of erythrolytic stress, which accompanies many disease states, macrophages play key...
GSE154523: Dioxin Disrupts Dynamic DNA Methylation Patterns in Genes that Govern Cardiomyocyte Maturation [RNA-seq]
To test the hypothesis that the disruption caused by TCDD in cardiomyocytes results from changes in ...
GSE107620: Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma [RNA-Seq]
PD-L1 is a ligand for the inhibitory PD1 receptor on T cells and its expression in some cancers inhi...
GSE154159: scRNA-seq of electrophysiologically characterized mechanosensetive DRG neurons reveals maturational differences in gene expression
Cultured dorsal root ganglia neurons of 4 and 12 weeks old C57Bl/6 mice were first characterized as ...
GSE156306: Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin accessibility and looping [RNA-Seq 2]
During the human cord blood CD34+ cell differentiation, expression of the genes which contribute to ...
GSE145314: Loss of Tmem106b leads to myelination deficits: implications for FTD treatment strategies
Genetic variants that define two distinct haplotypes at the TMEM106B locus have been implicated in m...
GSE150008: TGF-1 licensed murine mesenchymal stromal cells show superior therapeutic efficacy in modulating corneal allograft immune rejection in vivo
We report a novel licensing strategy to improve the immunosuppressive capacity of MSCs. Licensing mu...
GSE153833: Differential gene expression in the tumorigenic liver of Nod2-/- and wild type mice
We report that Nod2, a pattern recognition receptor, protects from high fat diet-dependent liver mal...
GSE59621: A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells
In this study we report the discovery of an unexpected nuclear activity of small RNAs that target an...
GSE52447: Transcriptome-wide mapping of human Staufen1 binding sites
Purpose: We performed RNA-Immunoprecipitation in Tandem (RIPiT) experiments against human Staufen1 (...
GSE154449: RNA-seq analysis of PRMT5 targeted genes in Tu686 cells
RNA-seq was performed to identify transcriptional targets of PRMT5 in Tu686 cells treated with shPRM...
GSE154217: GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner
A reduction in hepatocyte GH-signaling promotes non-alcoholic fatty liver disease (NAFLD). However, ...
GSE156288: T-bet and STAT6 Coordinately Suppress the Development of IL-9-mediated Atopic Dermatitis-like Skin Inflammation in Mice
T-bet and STAT6 are critical factors for helper T cell differentiation in humans and mice. Additiona...
GSE153852: KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma
The goal of this study was to define functional and gene regulatory effects of KDM3A and Ets1, and t...
GSE153887: Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
We report a new method for culturing patient breast tumor cells in vitro, for subsequent transplanta...
GSE146900: Quantitative Analysis of Wild Type and CTGF-/- Retinal Transcriptomes During Postnatal Vascular Development
Purpose: The goal of this study is to compare the retinal transcriptomes of wild-type and CTGF-/- m...
GSE146437: Embryonic lethality and defective mammary gland development in activator function impaired conditional knock-in ErbB3V943R mice
ERBB3, a pseudo-kinase domain containing human epidermal growth factor receptor (ERBB/HER) family me...
GSE151936 (mouse): C9orf72 in myeloid cells suppresses STING-induced inflammation
In this study we report that loss of C9orf72 expression in myeloid cells drives STING/type I interfe...
GSE157212: Quercetin promotes in vitro maturation of oocytes from humans and aged mice
The flavonol compound quercetin is considered to be an anti-aging agent due to its cytoprotective ac...