PLX102797

GSE51005: Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

Early chemotherapy for advanced/metastatic non-castration resistant prostate cancer (PCa) may improve overall patient survival. We studied the safety, tolerability and early efficacy of up-front docetaxel chemotherapy and androgen deprivation therapy (ADT) versus ADT alone for patients with newly-diagnosed advanced/metastatic PCa. As proof of concept, we undertook in vivo gene expression profiling by next generation RNA sequencing (RNA-Seq). SOURCE: Ian Sudbery (ian.sudbery@dpag.ox.ac.uk) - CGAT MRC-FGU

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