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Automated Single cell RNA-seq analysis platform

Dissect heterogeneity at the single-cell level. Use flexible preprocessing workflows in Pluto scRNA-seq and analyze individual cell gene expression profiles, uncovering cellular diversity and function by cell type, condition. Single-cell RNA sequencing (scRNA-seq) is a powerful technique for examining the gene expression of individual cells, providing unprecedented insights into cellular diversity and function within complex biological systems. By analyzing gene expression at the single-cell level, researchers can identify novel cell types and states, track developmental processes, and understand mechanisms of disease progression. Pluto Bio's platform streamlines scRNA-seq data analysis, offering scalable, secure, and user-friendly tools for transformative biological insights.

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Unlocking cellular complexity with Pluto

Pluto simplifies the complexity of scRNA-seq data analysis. Our platform provides an integrated solution for processing, analyzing, and visualizing single-cell data. From identifying cell types to uncovering gene expression patterns, Pluto empowers researchers to gain deep insights into the cellular mechanisms driving biological processes and disease states.

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Empower your research with cutting-edge analytics

Pluto's advanced analytics engine enables researchers to seamlessly navigate the intricacies of single-cell data. Leverage our intuitive tools to perform differential expression analysis, cluster identification, and trajectory inference, all within a collaborative and secure cloud environment.

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Accessible single-cell genomics

With Pluto, accessing the power of scRNA-seq analysis doesn't require computational expertise. Our user-friendly platform breaks down barriers, allowing scientists from diverse backgrounds to explore the cellular landscape, drive discovery, and accelerate innovation in genomics research.

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Why scRNA-seq?

High-resolution insights

  • Single-cell level analysis
  • Uncover cellular heterogeneity and rare cell populations

Streamlined data integration

  • Harmonize scRNA-seq data with other omics data
  • Facilitate comprehensive multi-omics analyses

Advanced analytical tools

  • Pre-built and custom pipelines
  • Easy-to-use interfaces for complex analyses
  • No coding skills required for advanced data interpretation

Resources & Updates

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Learning Series
The Hidden Barriers Slowing Translational R&D with Single-Cell Data

Single-cell data is transforming translational research. From oncology to immunology, the ability to resolve cell populations at unprecedented resolution is fueling breakthroughs in target discovery, biomarker identification, and patient stratification.

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Learning Series
Comparing bioinformatics platforms: Pluto Bio, Partek Flow, Basepair, and Rosalind

Compare top bioinformatics platforms—Pluto Bio, Partek Flow, Basepair, and Rosalind—to find the best fit for your NGS data analysis needs. Assess supported assays, analyses, visualizations, and collaboration features.

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Learning Series
Understanding RNA-seq and scRNA-seq: A guide for biologists

Discover the differences between RNA-seq and scRNA-seq, their applications in target discovery, and how pseudobulking bridges bulk and single-cell analysis. Unlock insights into gene expression for drug development and personalized medicine.

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Learning Series
Unlocking biological insights with multi-omics approaches

Explore how multi-omics integrates diverse datasets like RNA-seq, ATAC-seq, and ChIP-seq to unlock biological insights, accelerate drug discovery, and drive personalized therapies. Learn more about its impact on cancer research and target identification.

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Learning Series
Alternatives to Rosalind for Bioinformatics and Computational Biology

Discover top alternatives to Rosalind for bioinformatics and computational biology. Explore platforms like Pluto Bio, BaseSpace, GenePattern, and more to find the right solution for your research needs.

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Learning Series
Annotating cell clusters in single cell RNA-seq datasets

Confidently annotate scRNA-seq clusters with strategies using gene sets, AI tools, and a biology-first approach to uncover cell types and states.

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Learning Series
RNA-Seq 101 for Biologists

Learn the basics of RNA-seq, including its methodology, applications, experimental design, and data analysis techniques. This 101 overview is perfect for biologists and bioinformaticists investigating transcriptomics for the first time.

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Product Updates
Announcing end-to-end single cell RNA-seq analysis in Pluto

Ready to experience the most intuitive scRNA-seq experience yet?

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Learning Series
The Origins, Comparisons, and Practical Insights into PRO-seq Technology

Dive into the world of Precision Run-On sequencing (PRO-seq) in this comprehensive blog post. Discover the origins of PRO-seq, how it compares with traditional RNA-seq, and explore a step-by-step guide on conducting a PRO-seq experiment. Uncover how this innovative technology is advancing our understanding of transcriptional dynamics and revolutionizing genomic research.

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Learning Series
Navigating RNA-Seq Data: A Comprehensive Guide to Normalization Methods

RNA sequencing (RNA-Seq) has revolutionized the way we study gene expression. The data deluge it produces, however, presents a critical question: how can we make valid comparisons between different samples or conditions?

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Learning Series
Differential Expression Analysis: Understanding the Techniques and Benefits in Research

Differential expression analysis is a powerful tool used to identify genes or transcripts that are differentially expressed between two or more conditions or sample types. This technique is commonly used in the field of genomics, transcriptomics, and proteomics to study the molecular mechanisms underlying different biological processes, such as disease development, response to treatment, or adaptation to different environments.

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Learning Series
DESeq2: An Overview of a Popular RNA-Seq Analysis Package

DESeq2 is a popular and widely used package in the field of bioinformatics for the analysis of RNA-Seq data. It provides a more comprehensive view of gene expression compared to traditional microarray technology.

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