Dissect heterogeneity at the single-cell level. Use flexible preprocessing workflows in Pluto scRNA-seq and analyze individual cell gene expression profiles, uncovering cellular diversity and function by cell type, condition. Single-cell RNA sequencing (scRNA-seq) is a powerful technique for examining the gene expression of individual cells, providing unprecedented insights into cellular diversity and function within complex biological systems. By analyzing gene expression at the single-cell level, researchers can identify novel cell types and states, track developmental processes, and understand mechanisms of disease progression. Pluto Bio's platform streamlines scRNA-seq data analysis, offering scalable, secure, and user-friendly tools for transformative biological insights.

Pluto simplifies the complexity of scRNA-seq data analysis. Our platform provides an integrated solution for processing, analyzing, and visualizing single-cell data. From identifying cell types to uncovering gene expression patterns, Pluto empowers researchers to gain deep insights into the cellular mechanisms driving biological processes and disease states.
Learn morePluto's advanced analytics engine enables researchers to seamlessly navigate the intricacies of single-cell data. Leverage our intuitive tools to perform differential expression analysis, cluster identification, and trajectory inference, all within a collaborative and secure cloud environment.
Learn moreWith Pluto, accessing the power of scRNA-seq analysis doesn't require computational expertise. Our user-friendly platform breaks down barriers, allowing scientists from diverse backgrounds to explore the cellular landscape, drive discovery, and accelerate innovation in genomics research.
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Single-cell data is transforming translational research. From oncology to immunology, the ability to resolve cell populations at unprecedented resolution is fueling breakthroughs in target discovery, biomarker identification, and patient stratification.
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Confidently annotate scRNA-seq clusters with strategies using gene sets, AI tools, and a biology-first approach to uncover cell types and states.
Learn the basics of RNA-seq, including its methodology, applications, experimental design, and data analysis techniques. This 101 overview is perfect for biologists and bioinformaticists investigating transcriptomics for the first time.
Ready to experience the most intuitive scRNA-seq experience yet?
Dive into the world of Precision Run-On sequencing (PRO-seq) in this comprehensive blog post. Discover the origins of PRO-seq, how it compares with traditional RNA-seq, and explore a step-by-step guide on conducting a PRO-seq experiment. Uncover how this innovative technology is advancing our understanding of transcriptional dynamics and revolutionizing genomic research.
RNA sequencing (RNA-Seq) has revolutionized the way we study gene expression. The data deluge it produces, however, presents a critical question: how can we make valid comparisons between different samples or conditions?
Differential expression analysis is a powerful tool used to identify genes or transcripts that are differentially expressed between two or more conditions or sample types. This technique is commonly used in the field of genomics, transcriptomics, and proteomics to study the molecular mechanisms underlying different biological processes, such as disease development, response to treatment, or adaptation to different environments.
DESeq2 is a popular and widely used package in the field of bioinformatics for the analysis of RNA-Seq data. It provides a more comprehensive view of gene expression compared to traditional microarray technology.