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Sequencing-based assays (Page 144)

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Explore curated data sets and assays

Sequencing-based assays (Page 144)

Figure 3b: HLA-DR+ CD14hi monocytes

Figure 3d: HLA-DR expression mDC

GSE78151: The transcriptome of central nervous system myelin

GSE76458: The transcriptome of central nervous system myelin

GSE137611: TET1-mediated DNA hydroxy-methylation regulates adult remyelination

GSE127880: Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-CTF (C99)

GSE121066: Trisomy of a Down syndrome critical region globally amplifies transcription via HMGN1 overexpression [proB RNA-Seq]

GSE126910: mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy

GSE64840: Questioned validity of GEDDs in DS

GSE52249: Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq]

GSE128621: RNASeq of White Blood Cells and PaxRNA tubes from indiviuals with T21 [strand-specific]

GSE101942: Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21

GSE121070: Trisomy of a Down syndrome critical region globally amplifies transcription via HMGN1 overexpression [SLAM-Seq]

GSE121065: Trisomy of a Down syndrome critical region globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq]

GSE131249: RNA-seq of human aneuploid cell lines with Trisomy 21

GSE125837: Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation (bulk)

GSE55504: Domains of genomewide gene expression dysregulation in Down syndrome [RNA-seq]

GSE112250: Promoter or enhancer activation by CRISPRa rescues haploinsufficiency caused obesity

GSE112125: Leptin responsive neurons

GSE114298: Targeting EZH2 reprograms intratumoral regulatory T cells to enhance cancer immunity

Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies (GSE106420)

Human tissue-resident memory T cells are defined by core transcriptional and functional signatures in lymphoid and mucosal sites (GSE94964)

Altered infant T cell differentiation in infection or vaccination reduces lung tissue-resident memory generation (GSE101696)

Tissue determinants of human NK cell development, function and residence (GSE133383)

Transcriptional control of influenza-specific CD4+ tissue-resident memory T cell generation (GSE137386)

GSE71058: Gene expression profiling in dentate granule cells from patients with mesial temporal lobe epilepsy with or without hippocampal sclerosis

GSE74065: Rapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming

GSE138100: Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis

GSE99307: Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity

GSE134697: Hippocampal and neocortex transcriptome sequencing data from 17 mesial temporal lobe epilepsy patients and 2 neocortex samples from neurologically healthy controls

GSE140393: Glia-specific nuclei isolation and single cell transcriptomics inform astrocyte pathology in human temporal lobe epilepsy

GSE133929: CRISPRa-mediated Kcna1 upregulation decreases neuronal excitability and suppresses seizures in a rodent model of temporal lobe epilepsy [II]

GSE138370: Changes in calcium homeostasis and gene expression implicated in epilepsy in hippocampi of mice overexpressing ORAI1

GSE70935: Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes

GSE99937: Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

GSE90766: Comprehensive transcriptomes of mouse pancreatic beta cells that transdifferentiated from alpha cells

GSE106709: RNA Sequencing for reprogrammed beta cells

GSE44875: Transcriptome profiling of human pancreatic lineage specification using RNA-seq

GSE90767: Comprehensive transcriptomes of mouse pancreatic beta cells that transdifferentiated from delta cells

GSE54973: Comprehensive mouse alpha and beta cell transcriptomes

GSE87530: Transcriptome comparison of PAX6 ablated mouse beta cells to WT beta cells, ChIP-seq analysis of PAX6 bound sites both in mouse and human beta cell lines (Min6 and EndoC), and ChIP-seq analysis of histone mark H3K9ac on mouse pancreatic beta cells.

GSE126375: PAX5 belongs to a functional transcription factor network commonly targeted in B-lineage leukemia (murine)

GSE79457: Converting adult pancreatic -cells into -cells by targeting Dnmt1 and Arx

GSE78966: Progenitor Cell Marker Aldehyde Dehydrogenase 1a3 Defines a Subset of Failing Pancreatic Beta Cells in Diabetic Mice

GSE131527: A composite immune signature parallels disease progression across T1D subjects (RNA-Seq Cohort 2 Cell Sorted)

GSE95376: RNA-Sequencing Reveals Genome-Wide LncRNAs Profiling Associated with Early Development of Diabetic Nephropathy

GSE131320: Human Islet Response to Selected Type 1 Diabetes Associated Bacteria

GSE123177: Gene expression profiles of glomerular endothelial cells support their role in the glomerulopathy of diabetic mice

GSE106148: Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

GSE123658: Transimmunom whole blood RNA-seq data from type 1 diabetic patients and healthy volunteers

GSE85530: Partially exhausted CD8+ T cells are associated with clinically beneficial response to Teplizumab in new onset type I diabetes (bulk RNA-seq of sorted CD8+ T-cells)

GSE78922: Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression

GSE64655: A Cell-based Systems Biology Assessment of Human Blood to Monitor Immune Responses After Influenza Vaccination

GSE83467: Mouse pooled LNEPs, pre- and post-influenza - Local lung hypoxia determines epithelial fate decisions during alveolar regeneration

GSE117637: Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency

GSE49366: EGR2 is Critical for Peripheral Nave T cell Differentiation and the T-Cell Mediated Response to Influenza

GSE85316: Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Bcl6-/- helper T cell Transcriptomes

GSE120542: Monocyte-derived alveolar macrophages induced by influenza infection confer long-term antibacterial protection [RNA-seq]

GSE61517: Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions

GSE119029: STAT2 Signaling Regulates Macrophage Phenotype during Influenza and Bacterial Super-infection

GSE75699: Transcriptome profiling of influenza virus-infected human bronchial epithelial cells

GSE49932: RNA-Seq global gene expression of four Dendritic cells subpopulations from lung (CD8+ and CD8- pDCs, CD103-CD11b+ and CD103+CD11b- cDCs) of influenza infected mice at four time points following infection

GSE96870: The effect of upper-respiratory infection on transcriptomic changes in the CNS

GSE118111: Transcriptome profiling of influenza-specific memory CD8 T cells in the lung airways, lung parenchyma, and spleen

GSE97949: A549 cell transcriptome responses to infection with H7N9 influenza virus

GSE116500: Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination

GSE89008: Human tracheobronchial epithelial (HTBE) cell transcriptome response to infection with H1N1, H3N2, and H5N1 influenza virus.

GSE114588: Characterization of antibiotic resistance and host-microbiome interactions in the human upper respiratory tract during influenza infection [human host RNA-seq]

GSE109099: Next Generation Sequencing Facilitates Quantitative Analysis of the Effect of GM-CSF on the Transcriptomes of Alveolar and Exudative Lung Macrophages from Influenza-infected C57BL/6 Mice

GSE107488: Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

GSE114232: Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomesof Wild Type , RIG-I-/-, MAVS -/- mice during influenza infection

GSE85597: Extracellular Matrix Proteolysis by MT1-MMP is Associated with Influenza-Related Mortality

GSE107947: Dissection of influenza infection in vivo by single-cell RNA-sequencing

GSE117029: Circadian regulation of lung inflammation

GSE115952: Non-lytic clearance of influenza B virus from infected cells [RNA-seq]

GSE124578: RNA-seq on Fixed and Permeabilized Plasma cells

GSE38838: Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

GSE93999: Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4--D-glucopyranoside Treatment