PLX273316
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle (GSE74570)
- Organsim mouse
- Type RNASEQ
- Target gene
- Project Studies in RNA secondary structure and RNA-protein interactions (Brian D. Gregory Lab)
Lifelong overexpression of Nampt preserved muscle NAD levels and exercise capacity in aged mice support tissue-autonomous NAD homeostasis in maintaining muscle mass and function. SOURCE: Ian,M,Silverman (iansilv@mail.med.upenn.edu)-Brian D. Gregory Lab University of Pennsylvania
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