PLX095648

GSE138370: Changes in calcium homeostasis and gene expression implicated in epilepsy in hippocampi of mice overexpressing ORAI1

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project Epilepsy transcriptomics

We showed that the overexpression of ORAI1 in the neurons of murine brain leads to spontaneous occurrence of seizure-like events in aged animals by altering Ca2+ response. SOURCE: Bartosz Wojtas (bartoszwojtas83@gmail.com) - Nencki Institute of Experimental Biology

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