PLX109134

The Poly(C) binding protein Pcbp2, and its retrotransposed derivative Pcbp1, are independently essential to mouse development (GSE72491)

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project Studies in RNA secondary structure and RNA-protein interactions (Brian D. Gregory Lab)

Pcbp1 and Pcbp2 are essential for mouse embryonic development and post-natal growth, Pcpb2 role in hematopoiesis, and Pcbp1 has evolved essential functions in the genome. SOURCE: Ian,M,Silverman (iansilv@mail.med.upenn.edu) - Brian D. Gregory Lab University of Pennsylvania

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