Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays (Page 137)
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE122631: Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4
Mammalian SWI/SNF complexes are multi-subunit chromatin remodeling complexes associated with an ATPa...
GSE122545: Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq]
Directed differentiation of induced pluripotent stem cells (iPSCs) towards specific lineages remains...
GSE125817: Transcriptomic responses of human monocyte-derived dendritic cells to HIV and other innate stimuli
Transcriptional programming of the innate immune response is pivotal for host protection. The transc...
GSE126169: MAIT cell RNA sequencing
Obesity underpins the development of numerous chronic diseases such as type II diabetes mellitus. It...
GSE123290: RNA-sequencing and CRISPR/Cas9 Screen of PEO1 cells grown in suspension.
RNA-sequencing of PEO1 cells grown in suspension (SUS1 and SUS3) was performed to evaluate transcrip...
GSE122568: Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation
DSCAM and DSCAML1 are immunoglobulin and cell adhesion-type receptors serving important neurodevelop...
GSE133854: Single-cell transcriptome analysis of uniparental embryos reveals parent-of-origin effects on human preimplantation development [RNA-seq]
To investigate the contribution of parental genomes to early embryogenesis, we systematically profil...
GSE126009: Derivation of primodial germ cell-like cells from induced pluripotent stem cells of patients with idiopathic azoospermia
At present, the etiology of most non-obstructive azoospermia (NOA) remains unclear, and the patients...
GSE138496: A FOXL2C134W/SMAD Complex Drives a Cancer Stem Cell Signature in Granulosa Tumors
The FOXL2 mutant C134W occurs in virtually all adult ovarian granulosa cell tumors (AGCT), and is co...
GSE122679: Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells
Glioblastomas (GBMs), which are the most deadly malignant brain tumors of children and adults, infil...
GSE124810: Epigenetic modulation of -cells by interferon- via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq]
Type 1 diabetes (T1D) is caused by autoimmune destruction of pancreatic cells. Mounting evidence su...
GSE128344: A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling]
Human iPS cells with different mutations linked to Alzheimer's Disease were differentiated into neur...
GSE145212: poly A+ RNA sequencing of quiescent and early serum stimulated control and MIR222HG-depleted WI-38s
We performed paired-end poly A+ RNA sequencing using total RNA isolated from serum-starved and seru...
GSE123608: Codon usage optimization in pluripotent embryonic stem cells [tRNA sequencing]
The uneven use of synonymous codons in the transcriptome regulates the efficiency and fidelity of pr...
GSE124903: mSWI/SNF functional genomic characterization of SMARCB1 mutants in SMARCB1-null and heterozygous settings
Chromatin remodeling complexes regulate gene expression by shifting, evicting, and exchanging nucleo...
GSE122736: Convergence of Cockayne Syndrome Group A and B Proteins at rRNA Transcription through Nucleolin Regulation
Cockayne Syndrome (CS) is a rare neurodegenerative disease characterized by short stature, cachexia,...
GSE124841: lncRNA n384546 promotes thyroid papillary cancer proliferation and migration by targeting miR-145-5p to regulate AKT3
we document a novel lncRNA, n384546, which may exert its oncogenic property in PTC tumorigenesis by ...
GSE127247 (human): Control of noncoding RNA production and histone levels by a 5 tRNA fragment
Small RNAs derived from mature tRNAs, referred to as tRNA fragments or tRFs, are an emerging class o...
GSE123649: Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease
Chronic inflammation driven by persistent antigenic challenge with dietary gluten permanently reshap...
GSE122649: Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [motor cortex]
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progre...
GSE128287: Reprogramming to human nave pluripotency mirrors pan-cancer DNA hypermethylation [RNA-seq]
Aberrant DNA hypermethylation of promoter CpG islands in the context of a hypomethylated genome is a...
GSE126078: The phenotypic diversity of treatment-refractory metastatic castration-resistant prostate cancer
The widespread and long-term use of potent therapies designed to repress androgen receptor (AR) sign...
GSE128143: Global Epigenomic and Transcriptomic changes associated with Human Retinal Pigment Epithelial Epithelial-to-Mesenchymal Transition in a Stem Cell-based model of Epiretinal Membrane Formation (RNA-seq)
Epithelial to mesenchymal transition (EMT) is a biological process involved in tissue morphogenesis ...
GSE136151: Opposing functions of BRD4 isoforms in breast cancer
Bromodomain-containing protein 4 (BRD4) is a cancer therapeutic target in many ongoing clinical tria...
GSE128331: HNF1A deficiency impairs -cell fate, granule maturation and function
Mutations in HNF1A cause Maturity Onset Diabetes of the Young type 3, the second most frequent form ...
GSE126379: Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs)
Genome wide association studies have identified >200 susceptibility loci accounting for much of the ...
GSE126868: Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis
The chemical diversification of natural products provides a robust and general method for creation o...
GSE131594: Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway [DMSO vs DORMANT]
Eradicating tumor dormancy that develops following oncogene-targeted therapy, including after epider...
GSE127072: Transcriptomic analysis of HOK following interaction with diploid and haploid Candida albicans strains
A comprehensive RNASeq analysis was performed on Primary Human Oral Keratinocytes following their in...
GSE129893: CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE]
CRISPR-guided DNA base editors enable the efficient installation of targeted single-nucleotide chang...
GSE126358: SURF1 mutations causative of Leigh syndrome impair human neurogenesis [polyA RNA-seq]
Mutations in the mitochondrial complex IV assembly factor SURF1 represent a major cause of Leigh syn...
GSE126155: ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia
Familial dysautonomia (FD) is a recessive neurodegenerative disease caused by a splice mutation in E...
GSE131662: RNAseq of GFP-sorted cells (Low-GFP vs. High-GFP, GFP-fed vs GFP+fed)
RNAseq analysis of cells that have accumulated post-abscission midbodies SOURCE: Rytis Prekeris (ryt...
GSE123973: Metabolism as an early predictor of DPSCs aging
Pluripotent stem cells can switch their unique metabolic requirements to facilitate cellular changes...
GSE126207: Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance
The oncoprotein transcription factor MYC is overexpressed in the majority of human cancers. Key to i...
GSE124085: Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium
The genetic regulatory network controlling early fate choices during human blood cell development ar...
GSE124858: Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [scRNA-seq]
Background Bone marrow stromal cells (BMSCs) are a heterogeneous population that participates in wou...
GSE125066: Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation
TgIST is an effector secreted by Toxoplasma gondii into the host cell that translocates to the nucle...
GSE129843: Short-Term Time-Restricted Feeding Alters Rhythmicity of Lipid and Amino Acid Metabolites in Overweight Men
Time-restricted feeding improves metabolic health independently of dietary macronutrient composition...
GSE126736: ribosome profiling of cell line models of human breast cancer
We performed ribosome profiling in cell line models of human breast cancer. We profiled 2 representa...
GSE126917: Loss of CHD1 promotes chromatin dysregulation leading to heterogeneous mechanisms of resistance to hormone therapy in prostate cancer [RNA-seq]
Next generation androgen receptor (AR) signaling inhibitors have significantly improved the survival...
GSE124843: Integrative transcriptomic analysis reveals mechanisms controlling the reciprocity of epithelial and mesenchymal genes during epithelial-to-mesenchymal transition
Epithelial-to-mesenchymal transition (EMT) is an important developmental process that is also activa...
GSE126353: A PKA/PP2A AXIS DRIVES THE GROWTH OF NEUROENDOCRINE SCLC
Small cell lung cancer (SCLC) is an aggressive subtype of lung cancer whose biology is still poorly ...
GSE128189: Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
Small intestinal bacterial overgrowth (SIBO) has been implicated in symptoms associated with functio...
GSE130117: Simultaneous measurement of DNA repair activities and mRNA abundance in single cells
New methods that measure the static abundance of DNA, RNA, and proteins in single cells are rapidly ...
GSE124824: RNA-seq in 247 B-lineage ALL
RNA-seq from RNA isolated from bone marrow or peripheral blood of newly diagnosed acute lymphoblasti...
GSE128113: Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons
Host defense by the innate immune system requires the establishment of antimicrobial states allowing...
GSE126779: Human prostate cancer cell lines treated with BET Bromodomain inhibitor JQ1
RNA-Sequencing data for DU145 and PC3 cell lines treated with two concentrations of JQ1 in combinati...
GSE133887 (human): Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis
Tumor microenvironment-targeted therapies are emerging as promising treatment options for different ...
GSE124437: Transcriptomic Profiling of Circulating Tumor Cells in Multiple Myeloma: A New Model to Understand Disease Dissemination III
The number of peripheral blood (PB) circulating tumor cells (CTCs) predicts risk of transformation i...
GSE136200: RNA-sequencing of specific peripheral blood mononuclear cells in sepsis
We here sought to better understand the transcriptomic alterations in sorted monocytes (CD14+), CD4+...
GSE129842: Deciphering the m6A code via quantitative profiling of m6A at single-nucleotide resolution [III]
N6-methyladenosine (m6A) is the most abundant modification on mRNA, and is implicated in critical ro...
GSE131601: Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway [YAP1 KO vs CTRL]
Eradicating tumor dormancy that develops following oncogene-targeted therapy, including after epider...
GSE125182: System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection
The compendium of RNA-binding proteins (RBPs) has been greatly expanded by the development of RNA in...
GSE126409: Dynamic and distinct transcriptional response of CD8+ cytotoxic T lymphocytes to tissue alarmins and adaptive cytokines
The respective effects of tissue alarmins like interleukin (IL)-15 and interferon beta (IFNb), and c...
GSE125086: Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors
Aberrant translation initiation at non-AUG start codons is associated with multiple cancers and neur...
GSE124164: GATA factor-mediated gene regulation in human erythropoiesis (RNA-Seq)
Human erythropoiesis is a stepwise process in which multipotent hematopoietic stem/progenitor cells ...
GSE124857: LSD1 transcriptome analysis in Merkel cell carcinoma (MCC) cell lines
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine cancer of the skin, caused by either exc...
GSE128056: Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer
The results from our study have identified two clinically relevant, divergent and druggable pathways...
GSE125112: Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes
Combined treatment with all-trans retinoic acid and GSK2879552 results in synergistic effects on gen...
GSE124227: ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq)
Mutations in ARID1A, a subunit of the SWI/SNF chromatin remodelling complex, are the most common som...
GSE130140: Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
The three-dimensional genome organization is critical for gene regulation and can malfunction in dis...
GSE124189: The mevalonate pathway is required for pyrimidine synthesis and survival of p53-deficient colon cancer cells in metabolically compromised environments
In this study, we have investigated the effect of p53 deletion on the metabolic activity of colon ca...
GSE124199: Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma
Lung adenocarcinoma (LUAD)-derived oncogenic Wnts increase cancer cell proliferative/stemness potent...
GSE125014: Molecular determinants for enzalutamide-induced transcription in prostate cancer
Enzalutamide, a second-generation androgen receptor (AR) antagonist, has demonstrated clinical benef...
GSE125369: Epithelial mesenchymal transition (EMT) in A549 NSCLC cells. TGFbeta was used to induce EMT, RNA isolated and subjected to RNAseq on Illumina HiSeq
The capacity of cancer cells to undergo epithelial mesenchymal trans-differentiation has been implic...
GSE128359: Small non-coding RNA profiling in human biofluids from healthy individuals
The role of non-coding RNAs in different biological processes and diseases is continuously expanding...
GSE124556: Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq)
The pervasive nature of RNA polymerase II (Pol II) transcription requires efficient termination. A k...
GSE125372: Widespread transcriptional scanning in the testis modulates gene evolution rates
The testis expresses the largest number of genes of any mammalian organ, a finding that has long puz...
GSE131593: Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets
Myelofibrosis is a severe myeloproliferative neoplasm characterised by increased numbers of abnormal...
GSE126475: Exploring ILF2 regulatory genes by next-generation sequencing
We knocked down the expression of ILF2 in the A549 cell line and sequenced the RNA genes with the un...
GSE133054 (human): mRNA sequencing of mouse and human heart tissue
We deposit the data of single-cell and bulk-cell rna-seq of normal mouse heart. In addition, we cond...
GSE124263: Neonatal and adult human testis defined at the single-cell level
Spermatogenesis has been well studied in rodents and invertebrates, but remains poorly understood in...
GSE138441: Knockout ofStaufen1 impairs the localization of specific subsetsof mRNAs on the mitotic spindle of colorectal cancer cells
Staufen1 (STAU1) is an RNA-binding protein involved in maturation, localization, translation and dec...
GSE142405: Rational and scalable strategies to identify small molecular glue degraders
In our effort to characterize putatite novel molecular glues that we found in a phenotypic screen, ...
GSE124197 (human): A Genome-wide CRISPR Screen Identifies Novel Genes Reinforcing Human Aging
A variety of cellular stresses including telomere erosion, genomic instability, DNA damage and heter...
GSE124198: Comprehensive analysis of RNA-seq kits for standard, low and ultra-low quantity samples
High-throughput RNA-sequencing has now become the gold standard method for whole-transcriptome gene ...
GSE126535: A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-B
The non-canonical NF-B signaling cascade is essential for lymphoid organogenesis, B-cell maturation,...
GSE128351: Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination
The SWI/SNF complex is a critical regulator of pluripotency in human embryonic stem cells (hESCs), a...
GSE126488: IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche
Our understanding of signalling pathways that regulate human pluripotent epiblast cells is limited, ...
GSE128229: Profiling of Myometrium and Leiomyoma transcriptomes in 15 leiomyoma (MED12 G44 mutant) and 15 matched normal myometrium (WT) patient tissue samples.
Through comprehensive profiling of transcribed genes in myometrium and leiomyoma tissue samples, we ...
GSE130853: Gene-Specific Control of tRNA expression by RNA Polymerase II (nascent RNA-seq)
Increasing evidence suggests that tRNA levels are dynamically and specifically regulated in response...
GSE131135: Synthetic lethal and resistance interactions with BET bromodomain inhibitors [scRNA-Seq]
BET bromodomain inhibitors (BBDI) are promising therapeutic agents in triple-negative breast cancer ...
GSE130870: Nuclear RNA-seq of shRNA-mediated TARBP2 knockdown
To identify changes in splicing patterns following TARBP2 knockdown, RNA-sequencing was performed on...
GSE131147: Gene expression changes associated with resistance to tagraxofusp (SL-401)
The goal of this experiment was to determine the gene expression changes that occur in the setting o...
GSE124535: Gene expression profiles of 35 paired HCC and non-tumor tissues by RNA-seq data
This study aims to uncover the transcriptomic variations in HCC SOURCE: Li Zhang (15121014731@126.co...
GSE124308: Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons
Purpose: The transcriptional differences between iPSC-derived cortical neurons from patients with id...
GSE130865: RNA-seq of shRNA-mediated EXOSC10 and XRN2 knockdown
To identify changes in gene expression following EXOSC10 and XRN2 silencing, 3'-end RNA-sequencing w...
GSE126981: Effect of Salmeterol and Roflumilast N-oxide (RNO) alone and in combination on gene expression changes in BEAS-2B human airway epithelial cell line
RNA-sequencing was performed to study the effect of phosphodiesterase 4 inhibition by Roflumilast N-...
GSE126522: SLAM-seq for K562 endogenous mRNA decay
mRNA translation decodes nucleotide into amino acid sequences. However, translation has also been sh...
GSE129104: Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal
Differentiation of neural retina in organoid cultures from human pluripotent stem cells (PSCs) is hi...
GSE125121: RNA sequencing of host transcriptome of human foreskin fibroblast cells infected with either bradyzoites and tachyzoite of Toxoplasma gondii
The purpose of this data set is to determine if bradyzoites impact the host transcripton in a simila...
GSE124922 (human): TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells
RNA-seq analysis to understand the regulation of genes by TET1 in mouse lungs and human bronchial ep...
GSE124335: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
Microglia play critical roles in neural development and homeostasis. They are also implicated in neu...
GSE129436: Characterization of the transcriptional response to DNA in STING KO cells
Here we demonstrate that the SIDSP induces a broad and potent antiviral response that is abrogated b...
GSE130443: Progenitor-Derived Human Endothelial Cells Evade Alloimmunity by CRISPR/Cas9-Mediated Complete Ablation of MHC Expression
Purpose: To compare human progenitor cell-derived endothelial cells ablated of MHC molecules to endo...
GSE128342: Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9
Previous studies have identified frequent MLL-AF4 chromosomal translocation breakpoints in patients....
GSE128791: Bulk RNA sequencing of A375, BT549, SKBR3 and 315A cell lines [cell line bulk RNA-seq]
We first validated the robustness and high throughput capability of the GTO protocol in multiple cel...
GSE124350: Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease
BACKGROUND & AIMS: Intestinal mononuclear phagocytes (MNP) are phenotypically similar, but have diff...
GSE126502: Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [ABE-max]
CRISPR-Cas base editor technology enables targeted nucleotide alterations and is being rapidly deplo...