PLX256819

GSE128229: Profiling of Myometrium and Leiomyoma transcriptomes in 15 leiomyoma (MED12 G44 mutant) and 15 matched normal myometrium (WT) patient tissue samples.

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Through comprehensive profiling of transcribed genes in myometrium and leiomyoma tissue samples, we demonstrate two distinct gene expression profiles for myometrium and leiomyoma. This study shows that transcriptional dysregulation, and not post-transcriptional dysregulation, is primarily responsible for the perturbations of key biological processes in leiomyomas such as the extracellular matrix organization. SOURCE: Debabrata Chakravarti (debu@northwestern.edu) - Northwestern University

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