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Sequencing-based assays (Page 37)
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GSE72901: Histone arginine methyltransferase CARM1 Is Crucial for Epigenetic Regulation of Starvation-induced Autophagy
Autophagy is a highly conserved self-digestion process, essential to maintain homeostasis and viabil...
GSE123022: Deep single-cell RNAseq of postnatal day 7 microglia from wild type and Trem2 knockout brains
We generated single-cell RNAseq profiles of 369 microglia (183 from wild type and 186 from Trem2 kno...
GSE70883: Gene expression analyses of HB9-GFP D2 mMN cultures following Pbx1 exon 7 inclusion
PTBP1 and PTBP2 control alternative splicing programs during neuronal development, but the cellular ...
GSE65864: PATZ1 is a DNA damage responsive transcription factor that inhibits p53 function
Insults to cellular health cause p53 protein accumulation and loss of p53 function leads to tumorige...
GSE72937: The endfeetome, a astroglial translatome of the neurovascular unit
We aimed to identify astroglial transcripts preferentially translated in the neurovascular unit. The...
GSE71585: Adult mouse cortical cell taxonomy by single cell transcriptomics
Nervous systems are composed of numerous cell types, but the extent of cell type diversity is poorly...
GSE84145: Transcriptome profile of wildtype and Ret homozygote null mouse guts at E11.5 and E12.5
Total mRNA seq was perfomed on widtype and Ret null mouse embryonic gut at 2 stages of devlopment- E...
GSE71747: The DNA methylation landscape of human melanoma [RNA-Seq]
Melanoma genomes are often characterized by large numbers of sunlight-induced mutations. However, ep...
GSE71586: Multiple targeted metabolic effects of an oriental herb medicine Taeeumjowuitang with transcriptional response in diet-induced obesity; comparison with green tea extract
We investigated the effect of an oriental herbal medicine Taeeumjowuitang on phenotype characteristi...
GSE72631: Effects on the transcriptome upon deletion of distal elements are not correlated with the size of H3K27Ac peaks in human cells
Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associ...
GSE75059: Transcriptional profile changes by Prox1 expression in thyroid cancer cells
Human thyroid cancer cell line BCPAP was engineered for doxycyclin-mediated inducible expressoin of ...
GSE88967: Expression changes following conditional deletion of SMARCA4 (Brg) in mouse embryonic stem cells [RNA-seq]
We performed RNA-seq 72 h after acute deletion of Smarca4 in a line of conditional knockout mouse em...
GSE124313: Gene transcription and chromatin accessibility of conventional NK cells and ILC1s in spleens of uninfected and Toxoplasma gondii-infected Mice
RNA sequencing and ATAC-seq of conventional NK cells and ILC1s in uninfected mice and mice that were...
GSE89264: Transcriptional profile of mouse nephron progenitor cells
In developing mammalian kidney, nephron progenitor cells (NPC) give rise to all cells in mature neph...
GSE72784: Unique Broad Histone Lysine 4 Methylation Domains in Mouse Oocytes and Dynamic Regulation during Maternal to Zygotic Transition
The maternal to zygotic transition (MZT) involves the transfer of genome regulation from the oocyte ...
GSE72064: Genome-wide profilings of transcriptome and translatome in mouse hippocampi after contextual fear conditioning
Memory stabilization after learning requires transcriptional and translational regulations in the br...
GSE117559: RNA-sequencing of liver samples derived from offspring sired by males chronically exposed to alcohol prior to conception
Using an established mouse model of chronic exposure, previous work by our group had linked preconce...
GSE72321: Engrailed homeoprotein protects mesencephalic dopaminergic neurons from oxidative stress
Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engr...
GSE75714: RNA Sequencing Facilitates Quantitative Analysis of BV-2 Transcriptomes
Using RNA-seq, we report here that BV-2 microglial cells have a distinct transcriptomic signature an...
GSE71629: Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis
Despite the fact that the majority of lung cancer deaths are due to metastasis, the molecular mechan...
GSE67786: Endocardial Brg1 disruption illustrates the EMT origins of semilunar valve disease
Discreet defects during prenatal semilunar valve (SLV) development frequently progress to pathologic...
GSE72589: Transcriptome-wide Quantitative Analysis of XLPDR-derived human dermal fibroblasts with POLA1 deficiency
The goal of this study is to analyzed transcriptome changes caused by POLA1 deficiency. Our data rep...
GSE73277: hTERT promotes cell adhesion and migration independent of telomerase activity
We sequenced mRNA from 6 human cell lines stably over-expressed specific gene or empty vector, and s...
GSE75210: Simultaneous pathway activity inference and global gene expression analysis using RNA-sequencing [myd88]
Two 96-well plates per genotype wild type and Myd88 knockout, 4 hour time series in 0.5 hr incremen...
GSE66211: Mecp2: an unexpected regulator of macrophage gene expression and function [RNA-Seq]
Mutations in methyl-CpG-binding protein 2 (MeCP2), a major epigenetic regulator, are the predominant...
GSE107611: Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells
Whole transcriptome for PRMT6 knock-out and control NT2/D1 cells with and without ATRA (all-trans re...
GSE71943: RNASeq in mouse Alkbh1 KO and WT ESC
It has widely accepted that 5-methylcytosine is the only form of DNA methylation in mammalian genome...
GSE72293: Gene expression in the developing murine utricle
We report a gene expression changes during development and maturation of the murine utricle SOURCE: ...
GSE72699: Quantitative Analysis of Cardiomyocyte-specific Tbx20 Overexpression and Control Mouse Heart Transcriptomes Using Next Generation Sequencing
Purpose: The goals of this study is to determine the differential expression of transcriptome in car...
GSE72811: Functional Evidence Implicating Chromosome 7q22 Haploinsufficiency in Myelodysplastic Syndrome Pathogenesis
Purpose: 5A3+/del mice, which have a heterozygous germ line deletion of a 2-Mb interval of chromosom...
GSE73318: Gene expression analysis following JQ1 treatments in colon cancer lines
RNAseq is performed (50bp single end reads) on SW480, HT-29, HCT-15, HCT-116, COLO 205, and COLO 320...
GSE75215: RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells
We report the pro-leukemic activities of PRMT5 in AML partly via modulating the transcription of key...
GSE67207: Effect of estrogen and selective estrogen receptor modulators on a mouse model of fallopian tube epithelia, an ovarian cancer precursor
The fallopian tube epithelium is one of the potential sources of high-grade serous ovarian cancer (H...
GSE72403: Next Generation Sequencing Facilitates Quantitative Analysis of subcutaneous tumors untreated and treated with doxycycline for 4h to activate shST18
We report the transcriptome profiling (RNAseq) in hepatoblast-derived tumors, without (untreated) or...
GSE74630: RNA-Seq of Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice
We sequenced RNA from Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice. SOURCE: S...
GSE116115: Identification of mesenchymal progenitors in the early limb bud
Identification of progenitors populations through FACS in the early limb buds (E10.5 and E11.5) foll...
GSE75229: A Mammalian Enhancer trap Resource for Discovering and Manipulating Neuronal Cell Types
There is a continuing need for driver strains to enable cell type-specific manipulation in the nervo...
GSE72596: SMAD2/3 potentiate cell identity conversions with master transcription factors
The exogenous expression of master transcription factors (TFs) is a powerful and exciting approach t...
GSE72759: Defining the consequences of genetic variation on a proteome-wide scale
Genetic variation governs protein expression through both transcriptional and post-transcriptional p...
GSE72121: The neuron-specific transcription factor Myt1l represses many non-neuronal fates
Normal differentiation and induced reprogramming require; the activation of target cell programs and...
GSE79086: Analysis of the expression profile of skin macrophages FACS-sorted from mice overexpressing activin and/or oncogenes of human papilloma virus 8 in keratinocytes.
We have shown that activin promoted skin tumorigenesis in mice induced by the human papilloma virus ...
GSE72442: Chd8 mediates cortical neurogenesis through transcriptional regulation of cell cycle and Wnt signaling genes
De novo mutations in CHD8 are strongly associated with autism spectrum disorder (ASD), however the u...
GSE72764: RNAseq analysis of the duodenum of intestine-specific adult TN mutant mice
Aim: Transcriptional analysis of the duodenum of adult Nkx2.2flox/TN;Villin-Cre (TNint) mice versus ...
GSE71396: Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability
The rules of engagement between zinc finger transcription factors and DNA have been partly defined ...
GSE103714: Genomic imprinting of Xist by maternal H3K27me3
Maternal imprinting at the Xist gene is essential to achieve paternal allele-specific imprinted X ch...
GSE72815: Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing
Here we present an RNAseq analysis of human bone samples, obtained from iliac crest needle biopsies,...
GSE126749: GEF-H1-IRF5 mediated gene expression changes in BMDM by MDP recognition
The transcription factor IRF5 is essential for immune defense against pathogens. Here, the authors s...
GSE70732: A comprehensive examination of dynamic gene expression changes in the mouse brain during pregnancy and the postpartum period
The developmental transition to motherhood requires gene expression changes that alter the brain to ...
GSE75042: A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients
Tumor progression is associated with an immunosuppressive microenvironment that consists of several ...
GSE71843: Mouse Synovial Sarcoma Models
Compare transcriptomes from SS18-SSX1 and SS18-SSX2 tumors SOURCE: Kevin,B,Jones (kevin.jones@hci.ut...
GSE72480: Differential expression of GFP+ and RFP+ TriPyMT cells
Tri-PyMT cell is a breast tumor cell line established from Tri-PyMT (MMTV-PyMT/fsp1-Cre/Rosa26-RGFP)...
GSE75738: RNA sequencing of small number germ cells including primordial germ cells (PGCs) collected from female embryonic 12.5 day (E12.5), Female germline stem cells (FGSCs), Germinal-stage oocytes (GV oocytes) and Meiosis II oocytes (MII oocytes)
Mammalian oogenesis is an intricate and coordinated process involving dramatic changes in the transc...
GSE68360: Genome-wide expression profile of livers from mice fed HFD,SO-HFD or Viv chow [RNAseq]
Purpose: Aim of the study is to identify changes in hepatic gene expression induced by either a 40kc...
GSE75176: Comparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [RNA-Seq]
Nrf2(A502Y) mutant failed to recognize cis-element required for induction of Nrf2 target genes.To ex...
GSE72018: Long non-coding RNAs in B cells (RNA-Seq)
Using RNA sequencing and de novo transcript assembly, we identified 4516 lncRNAs expressed in 8 diff...
GSE72311: Refining mouse annotations via targeted RNA sequencing
In this work we aim to improve the understanding of the mouse transcriptome complexity, investigate ...
GSE72468: EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling
Epidermal Growth Factor Receptor (EGFR) gene amplification and mutations are the most common oncogen...
GSE93743: Adult bone marrow-derived progenitors give rise to decidual cells and are essential for implantation and pregnancy maintenance
Bone marrow (BM)-derived progenitor cells (BMDPCs) are known to migrate and give rise to endometrial...
GSE67867: Competition between DNA methylation and transcription factors determines binding of NRF1
Eukaryotic transcription factors (TFs) are key determinants of gene activity, yet they bind only a f...
GSE118206: Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage (RNA-seq)
Small cell carcinomas from different tissues exhibit transcriptional and epigenetic convergence and ...
GSE76140: Initial seeding of the embryonic thymus by an immune-restricted lympho-myeloid progenitor independently of Notch signaling
Gene expression analysis of purified thymopoiesis-initiating progenitors/early thymic progenitors, l...
GSE95755: Multi-cellular Transcriptional Profiling Reveals an Epigenetic Barrier to Adult Heart Regeneration
The inability of the adult mammalian heart to regenerate following injury represents a major barrier...
GSE73579: Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq
Background & aims: Polycystic liver disease (PLD) is an autosomal dominantly inherited disorder caus...
GSE67833: Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury
Heterogeneous pools of adult neural stem cells (NSCs) contribute to brain maintenance and regenerati...
GSE117623: The Liquid Liver Biopsy: Detection of Circulating Epithelial Cells in Liver Disease
Using a microfluidic device, circulating epithelial cells (CECs) were enriched from peripheral blood...
GSE73336: Transplantation of gastric organoid-derived spasmolytic polypeptide/TFF2-expressing metaplasia (SPEM) cell lineage promotes ulcer repair in the aged stomach
Background & Aims: Spasmolytic polypeptide/TFF2-expressing metaplasia (SPEM) is known to emerge foll...
GSE69858: Critical modulation of hematopoietic lineage fate by the PAR/bZIP transcription factor Hepatic Leukemia Factor
Blood cell formation is a tightly regulated process initiated from a rare population of multipotent ...
GSE92403: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency. (RNA-seq)
The mechanisms underlying enhancer activation and the extent to which enhancer-promoter rewiring con...
GSE78158: DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes
Ectopic expression of the double homeodomain transcription factor DUX4 causes facioscapulohumeral mu...
GSE75851: ILC progenitor CEL-seq
Here we identify the c-kit+ CILP population which generates all ILC subsets including NK cells, and ...
GSE73845 (mouse): Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS]
Cancer stem cells (CSC) dictate tumor cell heterogeneity in diverse cancer types and arise, in part,...
GSE75648: RNA-Seq of Lgr6 positive and negative cells in mouse mammary gland
Lgr6-positive cells have been shown to label stem/progenitors cells in several tissues including ton...
GSE111583: Functional characterizations of the Hippo pathway effectors YAP and TAZ
The Hippo pathway plays an important role in regulating tissue homeostasis, and its effectors YAP an...
GSE109728: Effect of ER-464195-01 on the gene expression in the intestine of mice.
Our previous study identified a small molecule, orally active ER-464195-01, inhibits the calreticuli...
GSE69484: Deficiency of microRNA miR-34a in pluripotent stem cells expands cell fate potential
Mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) exhibit a pluripotent d...
GSE73887: Identification of MEF2B, EBF1, and IL6R as chromosome bound targets of EBNA1 essential for EBV infected B-lymphocyte survival
EBNA1 is the EBV-encoded nuclear antigen required for viral episome maintenance during latency. EBN...
GSE69354: PGC reversion to pluripotency involves erasure of DNA methylation from imprinting control centers followed by locus-specific re-methylation
Primordial germ cells (PGCs) are fate restricted to differentiate into gametes in vivo. However whe...
GSE73362: Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells
The extremely low efficiency of human embryonic stem cell (hESC) derivation using somatic cell nucle...
GSE75591: miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq]
miRNA-1343 is an uncharacterized miRNA predicted to target a number of genes involved in epithelial ...
GSE73718: Transcriptome profiling of HEK 293T cells depleted of endogenous miRNAs
To assess the impact of AdV-VP55 mediated degredation of host miRNAs on the cellular transcriptome. ...
GSE67868: The Polycomb protein Pcgf2/Mel18 regulates mesoderm cell fate-specification of embryonic stem cells through multiple mechanisms
Polycomb complexes are essential regulators of stem cell identity, yet very little is known about th...
GSE79102: SC3-consensus clustering of single cell RNA-Seq data
We report a new unsupervised clustering tool for single cell RNA-seq data called SC3. We show that b...
GSE73552: Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver [RNASeq]
Diurnal oscillations of gene expression are a hallmark of rhythmic physiology across most living org...
GSE76143: Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells
Zinc finger and SCAN domain-containing 10 (Zscan10, also known as Zfp206) encodes a transcription fa...
GSE74720: Genetic Diversity Through RNA Editing: Apobec1-mediated RNA editing in bulk and single cell macrophages and dendritic cells
RNA editing is a mutational mechanism that specifically alters the nucleotide content in sets of tra...
GSE107016: Transcriptional Analysis of Wild Type and KLF4-/- Peritoneal Macrophages
Krppel-like factor 4 (KLF4) is a critical regulator of macrophage activation. Here, we report transc...
GSE104381: Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
Rare heterozygous coding variants in the triggering receptor expressed in myeloid cells 2 (TREM2) ge...
GSE77586: The histone demethylase KDM6A controls the mammary luminal lineage through enzyme-independent mechanisms
Mammary ducts and alveoli are composed of basal and luminal cells, with the fate and differentiation...
GSE122729: Robust generation of honemogeneous midbrain organoids with in vivolike cellular composition facilitates neurotoxin-based Parkinsons disease modeling
We could establish the advanced protocol for generating homogeneous and mature midbrain organoids by...
GSE85107: Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia
Homeobox (HOX) proteins and the receptor tyrosine kinase FLT3 are frequently highly expressed and mu...
GSE73803: Effect of LSD1 depletion on gene expression in oocytes
The objective of the experiment is to compare the transcriptomes of LSD1 knockout (KO) and control o...
GSE73693: Whole transcriptome sequencing of pluripotent or differentiating mESCs
Examination of PRDM15 binding targets and those of SIN3A in WT vs. Prdm15 KO mESCs SOURCE: Jingxian ...
GSE73845 (human): Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS]
Cancer stem cells (CSC) dictate tumor cell heterogeneity in diverse cancer types and arise, in part,...
GSE139372: RNASeq of Human Skin Tregs and CD4 Teffs from melanoma cutaneous tumors
The aim of the study was to analyze the transcriptional profile of Tregs and CD4 Teffectors present ...
GSE67991: RNA seq of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wildtype (Ffar3 WT) male mice
The short chain fatty acid (SCFA) receptor (free fatty acid receptor-3; FFAR3) is expressed in pancr...
GSE104633: RNA-sequencing of the Math1-Cre SmoM2 mouse genetic model of medulloblastoma
We investigated how misactivation of the Hedgehog (Hh) pathway causes medulloblastoma, and found tha...
GSE75234: Impact of H3.3K36M mutation on chondroblastoma cancer epigenome
Over 90% of chondroblastomas contain a heterozygous mutation replacing lysine 36 with methionine (K3...
GSE98250: Establishment and Characterization of a Novel Murine Submandibular Gland Epithelial Cell Line.
Gene expression analysis of spontenously immortalized mouse submandibular salivary gland epithelial ...
GSE104551: RNA-Seq Analysis of Dose-Dependent TCDD-Elicited Femoral Gene Expression in Male Mice
Dose-dependent femoral gene expression was examined following repeated exposure (every 4 days for 28...
GSE73857: Newly constructed network models of different WNT signaling cascades applied to breast cancer expression data
RNA-Seq profiling of MCF-7 and MDA-MB-231.; We profiled RNA expression in the estrogen-receptor-posi...