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Sequencing-based assays (Page 2)
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GSE112037: Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li)
Two prostate cancer cell lines. PC3E and GS689.Li SOURCE: Zijun Zhang (zj.z@ucla.edu) - Yi Xing UCLA
GSE44654: An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes (RNA-Seq)
Animal germ cells produce PIWI-interacting RNAs (piRNAs), small silencing RNAs that suppress transpo...
GSE45446: Brg1 Modulates Enhancer Activation and Polycomb-mediated Repression in Mesoderm Differentiation [RNA-Seq]
We investigated the global gene expression changes in normal and Brg1-deleted mesoderm differentiati...
GSE50760: Gene expression profiling study by RNA-seq in colorectal cancer
The objective of this study is to identify a prognostic signature in colorectal cancer (CRC) patient...
GSE129472: Gene expression profiles of Foxp3RFP (WT), Foxp3EGFPiCre (Foxp3-deficient) and Foxp3EGFPiCreRictor/ (Foxp3-deficient and Rictor deficient) Treg cells.
Comparaison of the transcriptomes of WT and Foxp3-deficient regulatory T cells from the spleen of f...
GSE46807: A TAF4 coactivator function for E proteins that involves enhanced TFIID binding
The multisubunit TFIID plays a direct role in transcription initiation by binding to core promoter e...
GSE47851: The transcription factor GATA3 is critical for the development of all IL-7Ra-expressing innate lymphoid cells (ILCs) and maintenance of type 2 ILCs
Innate lymphoid cells (ILCs) play critical roles during innate immune responses to pathogens and lym...
GSE45568: Systematic analysis of palatal transcriptome to identify cleft palate genes within TGFbeta3-knockout mice alleles: RNA-Seq analysis of TGFbeta3 Mice
Background: In humans, cleft palate (CP) accounts for one of the largest number of birth defects wit...
GSE120174: RNA sequencing of human mammary epithelial cells
Study of RNA expression changes in human mammary epithelial cells under TGFbeta1 induced epithelial ...
GSE81474: Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis
The corneal endothelium is composed of a monolayer of corneal endothelial cells (CECs), which is ess...
GSE48649: High-resolution chromosomal maps of Xist RNA reveal a two-step spreading mechanism during X-inactivation
The Xist long noncoding RNA (lncRNA) is essential for X-chromosome inactivation (XCI), the process b...
GSE47703: Differential programming of B cells in Aicda-/- mice [RNA-Seq]
We sequenced mRNA from naive, in vitro activated, and GC B cells obtained from both Aicda-/- and Aic...
GSE44157: Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [RNA-seq_siRNA_transfection]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we charact...
GSE57272: Conserved non-coding sequence 2 (CNS2) of the Foxp3 genomic locus is essential for the function and stability of regulatory T cells during their activation
Regulatory T (Treg) cells play an indispensable role in immune homeostasis. The development and func...
GSE112382: Polycomb repressive complex 1 (PRC1) role in skin epithelium development [Epi Ring1a/b dKO]
Polycomb repressive complexes (PRC) 1 and 2 are essential chromatin regulators of cell identity. PRC...
GSE45319: The glycogen scaffolding protein PTG coordinately regulates glycogen and lipid storage
Glycogen and lipid are major storage forms of energy that are tightly regulated by hormones and meta...
GSE156898: Inhibition of G-protein signaling in cardiac dysfunction of Intellectual Developmental Disorder with Cardiac Arrhythmia (IDDCA) syndrome.
Background: Pathogenic variants of GNB5 encoding the 5 subunit of the guanine nucleotide-binding pro...
GSE47497: Induction of a hemogenic program in mouse fibroblasts
Definitive hematopoiesis emerges during embryogenesis via an endothelial-to-hematopoietic transition...
GSE50739: Tgif1 regulates quiescence and self-renewal signaling pathways of hematopoietic stem cells (HSCs)
In this study we demonstrate that Tgif1 has a role in HSCs maintenance, self-renewal and quiescence....
GSE52870: Pax5 restoration in a mouse model of B progenitor acute lymphoblastic leukemia
Hypomorphic mutations of PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-AL...
GSE50896: Lympho-myeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells
An immune-restricted lymphomyeloid-primed progenitor with the capacity to contribute to both myeloid...
GSE48843: RNA-Seq analysis of primary AML specimens exposed to AhR modulating agents
The goal of the study was to identify genes that are directly or indirectly coregulated by the AhR p...
GSE125336: -catenin activation promotes immune escape and resistance to anti-PD-1 therapy in hepatocellular carcinoma
We study the role of CTNNB1 in immune escape in HCC. SOURCE: Amaia Lujambio (amaia.lujambio@mssm.edu...
GSE74938: RNA-seq profiling of mouse PGC (Mus musculus)
PGCs undergo two distinct stages of demethylation before reaching a hypomethylated ground state at E...
GSE57533: Altered epigenetic programming links intestinal inflammation to colon cancer (RNA-seq)
This study uses whole-transcriptome sequencing to characterize the transcriptomes of the AOM/DSS mou...
GSE125864: Analysis of the genomic landscape in ALK+ NSCLC patients identifies novel aberrations associated with clinical outcomes
Expression data of primary and metastasic tissues from ALK+ NSCLC patients (Anaplastic lymphoma kina...
GSE71674: A Co-repressor CBFA2T2 regulates pluripotency and germline development [RNA-seq]
In this experiment, we sought to determine how PRDM14 and CBFA2T2 regulate the transcriptome of mous...
GSE47540: The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages
Alternative splicing and mRNA editing are known to contribute to transcriptome diversity. Although a...
GSE140108: RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB)
We aim to identify differentially expressed genes between enasidenib and DMSO treated CD71+ erythroi...
GSE48480: Oncogenic Hras-dependent epidermal growth is inhibited following RNAi-mediated depletion of Ctnnb1 and Mllt6
Genome-wide RNAi screens in mice identified Ctnnb1 and Mllt6 as physiological regulators of HrasG12V...
GSE44359: High resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts
We report high resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts (...
GSE49994: mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines
We sequenced the total mRNA and translating mRNA (RNC-mRNA) of three hepatocellular carcinoma cell l...
GSE43041: The role of Ldb1 in hemangioblast development: genome-wide analysis shows that Ldb1 controls essential hematopoietic genes/pathways in mouse early development and reveals novel players in hematopoiesis (sequencing)
The first site exhibiting hematopoietic activity in mammalian development is the yolk sac blood isla...
GSE48933: Ribosome profiling reveals features of normal and disease-associated mitochondrial translation
Ribosome profiling and RNAseq data on human BJ fibroblasts and cybrid cells using an adapted ribosom...
GSE47735: Interplay of host microbiota, genetic perturbations, and inflammation promote local development of intestinal neoplasms in mice
The preferential localization of some neoplasms, such as serrated polyps, in specific areas of the i...
GSE58608: The human skeletal muscle transcriptome assessed with RNA sequencing
The amount of RNA sequencing data on skeletal muscle is very limited. We have analyzed a large set o...
GSE50934: Lysine-specific demethylase 1 controls beige adipogenesis
The aim of this study is to identify the LSD1 genome binding profile in adipocytes. SOURCE: Delphine...
GSE49601: Leucegene: ALL sequencing
RNA sequencing of human leukemia SOURCE: Guy Sauvageau Institute for Research in Immunology and Canc...
GSE48085: Genome-scale analysis in blood progenitor and mast cells reveals how lineage-affiliated transcription factors control distinct regulatory programs [ChIP-Seq/RNA-Seq Experiments]
Despite major advances in the generation of genome-wide binding maps, the mechanisms by which transc...
GSE49114: Murine Schistosoma-Induced Pulmonary Hypertension: RNA-seq Data
Whole lung RNA-seq of 8 mice with experimental Schistosoma-induced pulmonary hypertension, compared ...
GSE127572: Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients
RIPK1 is known to play an important role in TNF induced immune signaling. We have identified three ...
GSE109816: Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing
We studied the cell compositon of normal human heart by single-cell sequencing. Distint subgroups of...
GSE51424 (mouse): Cell type-specific ribosome profiling in vivo.
We report cell-type specific ribosome profiling in a mouse glioma model. SOURCE: Peter Sims (pas2182...
GSE52123: Reinstatement of developmental stage-specific GATA4 enhancers controls the gene expression program in heart disease
Through integration of GATA4 genome-wide occupancy and RNA-seq dataset in embryonic conditional knoc...
GSE50927: RNAseq on lungs from WT vs claudin 4 KO mice that underwent ventilator-induced lung injury
WT mice and claudin 4 KO mice were exposed to ventilator-induced lung injury (VILI) for 2 hours. We ...
GSE52564: An RNA-Seq transcriptome and splicing database of neurons, glia, and vascular cells of the cerebral cortex
Purpose: To better understand the function of the various cell types of the brain, we prospectively ...
GSE65487: Identification and Expression Patterns of Novel Long Non-Coding RNAs in Neural Progenitors of the Developing Mammalian Cortex
Long non-coding (lnc)RNAs play key roles in many biological processes. Elucidating the function of l...
GSE51733: RNAseq analysis of alternative splicing in PTBP2 knockout mouse brain
The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturati...
GSE102849: Mice Exposed to Bisphenol A Exhibit Depressive-like Behavior with Neurotransmitter and Neuroactive Steroid Dysfunction
We report here hippocampal RNA-seq data from adult (20 weeks) male offspring exposed to 0 mg (contro...
GSE144968: Sequencing of mRNA in AML cells upon ALKBH5 knockdown
To identify the potential mRNA targets of ALKBH5, we conducted RNA-seq of mRNA samples enriched from...
GSE151761: Innovations in primate interneuron repertoire
We report single-nucleus transcriptomes from brain regions in 5 species: mice: Frontal Cortex, V1, H...
GSE49906: Transcriptome modulation of ventricles, cardiomyocytes and cardiac fibroblasts during postnatal mouse development
During development the fetal heart undergoes a rapid and dramatic transition to adult function throu...
GSE65082: Ezh2 maintains proliferation, transcriptional integrity, and the timing of late differentiation during mouse retina development
We investigated the gene expression profile changes after Ezh2 conditional knockout in the mouse ret...
GSE51606: Transcriptome Sequencing During Mouse Brain Development Identifies Long Non-Coding RNAs Functionally Involved in Neurogenic Commitment
Transcriptome analysis of somatic stem cells and their progeny is fundamental to identify new factor...
GSE95463: RNA-seq analysis of gene expression in the liver of control and Mst1/2 deficient mice
RNA-sequencing results with livers obtained from control and Mst1/2 deficient mice SOURCE: Wantae K...
GSE156473: High throughput joint profiling of chromatin accessibility and protein levels in single cells [PBMC stimulation]
Recent technological advances have enabled massively parallel single-cell Assay for Transposase Acce...
GSE45785: Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53.
We applied in parallel RNA-Seq and Ribosome-profiling analyses to immortalized human primary BJ fibr...
GSE51619: Evaluation of TRAP-sequencing technology with a versatile conditional mouse model
Evaluation of TRAP-sequencing by comparing transcriptomes and translatomes of different organs and d...
GSE51984: RNA-Seq analysis of human adult peripheral blood populations
Generate transcriptomic atlas of healthy peripheral blood subpopulations SOURCE: Guy Sauvageau Insti...
GSE62228: Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq)
An emerging theme of gene regulation is the involvement of architectural chromosomal molecules in tr...
GSE51393: A microRNA-directed program of cytotoxic CD8+ T cell differentiation
Acquisition of effector properties is a key step in the generation of cytotoxic T lymphocytes (CTLs)...
GSE148970: Transcriptional analysis of resting T cells from human blood and skin
After activation, CD4+ T helper (Th) cells differentiate into functionally specialized populations t...
GSE139239: RNA sequecing of E0771 DDR1 WT/KO mammary tumor transplanted from Rag1-/- to C57BL/6 hosts
Purpose: The goals of this study are to compare mammary tumor transcriptome profiling with or witho...
GSE48519: 5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation
In mammals, cytosine methylation (5mC) is widely distributed throughout the genome but is notably de...
GSE148862: Peripheral blood non-canonical small non-coding RNAs as novel biomarkers in lung cancer and pulmonary tuberculosis (validation cohort)
One unmet challenge in current lung cancer diagnosis is to accurately differentiate lung cancer pati...
GSE95854: TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding
RNA sequencing (RNA-seq) offers a snapshot of cellular RNA populations, but not temporal information...
GSE54877: RNAseq of memory cocktail versus IL-2 grown OT-I CD8 T cells
Cytotoxic T cells are typically expanded ex vivo for adoptive immunotherapy by culture with IL-2. T...
GSE60599: Genome wide transcriptome analysis of skin harboring tissue-resident memory CD8+ T cells
Comparison of the transcriptional profiles of full-thickness murine skin harboring tissue resident m...
GSE53370: RNA m5C Methylation in breast cancer using MeRIP-Seq
RNA m5C methylation profile of MCF10A and MDA486 by using MeRIP-Seq protocol SOURCE: Xiaodong Cui (x...
GSE85201: TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation
Jurkat T cells were activated with PMA and ionomycin. Total and Labeled fragmented RNA was extracted...
GSE56473: rd10 transcriptome analysis
Retinitis pigmentosa (RP) is a photoreceptor disease that affects approximately 100,000 people in th...
GSE52662: m6A RNA modification controls cell fate transition in mammalian embryonic stem cells (RNA methylation)
Here we determine the map of RNA methylation (m6A) in mouse embrionic stem cells, and Mettl3 knock o...
GSE74397 (human): N6-methyladenosine-Mediated Nuclear Export of Messenger RNA
N6-methyladenosine (m6A) is the most common internal modification in eukaryotic messenger RNA (mRNA)...
GSE139335: MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer
Neuroendocrine prostate cancer (NEPC) is a highly aggressive malignancy of increasing prevalence wit...
GSE54447: Expression profiling of mouse T-ALL (Vav-tTA;TRE-GFP-shIkaros primary leukemia ALL101) cells following Ikaros restoration [RNA-Seq]
To examine Ikaros tumor suppressor mechanisms, we have utilized inducible RNAi to dynamically restor...
GSE114912: RNA-Seq of murine CD4 positive T cells isolated from Nur77-deficient mice and their Nur77-competent counterparts
Endogenous changes in the nuclear encoded genes were analysed using RNA-Seq in order to compare the ...
GSE142560 (mouse): Gene expression profile of HSPC with cell-intrinsic innate immune signaling activation after LPS treatment
The underlying mechanisms responsible for the competitive advantage of MDS HSPC in an inflammatory m...
GSE51933: Small RNA-sequencing of Fibro-Adipogenic Progenitors (FAPs) upon Histone Deacetylase inhibition in young mdx mice
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenera...
GSE53427: Kat2a regulates hippocampal memory formation [small RNA-seq]
We sequenced small RNAs from 12 samples extracted from mouse CA1 tissue to generate the first CA1-sp...
GSE52477: Lsh regulates LTR retrotransposon repression independent of Dnmt3b function (RNA-Seq)
Background: Global DNA methylation contributes to genomic integrity by supressing repeat associated ...
GSE57682: Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
Regulatory T (Treg) cells suppress the development of inflammatory disease, but our knowledge of tra...
GSE53150: RNAseq analysis of mature thymic NKT cells and immature thymic DN1eP cells
We report the identification of immature thymic CD4(-),CD8(-) double-negative (DN)1e cells with the ...
GSE58604: Human cortical transcriptome informs brain imaging
We carried out RNA-sequencing (RNA-seq) of adult human postmortem neocortical brain tissue, and then...
GSE53695: nELAVL HITS-CLIP in Alzheimer's Disease patients
Human brain samples from control and advanced Alzheimer's Diseased subjects were subjected to HITS-C...
GSE103761: RNA-seq analysis of uveal melanoma cells treated with FR900359
FR900359 is an allosteric inhibitor of Gq. 92.1 uveal melanoma cells, which are driven by constituti...
GSE54473: Transcriptionally repressive histone modifying enzymes a role in olfactory receptor expression
identification of a role for g9a and glp histone methyltransferases in the stochastic fate decision ...
GSE52525: Transcriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue
Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biolo...
GSE63772: RNA-Seq of retina and RPE/choroid tissues from wild type, Abca4 knockout and Abca4 L541P;A1038V knockin mice
We report RNA-Seq analysis of the transcriptome of retinas and RPE/choroids from Abca4 knockout, Abc...
GSE46490: High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA)
The granulosa cells in the mammalian ovarian follicle respond to gonadotropin signalling and are inv...
GSE52742: Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma
In this study we present the first genome-wide expression profiling of peripheral B cells by massive...
GSE62288: A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells
We describe a novel population of human adult cardiac resident stem cells (CRSCs), which are positiv...
GSE56284: Transcriptome profiling of severe spinal muscular atrophy mouse embryonic stem cell-derived motor neurons
Proximal spinal muscular atrophy (SMA) is an early onset, autosomal recessive motor neuron disease c...
GSE146899: Interaction with Cholangiocytes and Neutrophils
Alcoholic hepatitis (AH) is a life-threatening disease with limited treatment options. The presence ...
GSE53782: Gene expression profiling of the ileum following vertical sleeve gastrectomy compared to pair-fed sham surgery controls in mice with high-fat diet-induced obesity.
We report the expression profiles of ileal samples extracted from obese male C57Bl6 mice following v...
GSE45975: Bach2 represses effector programmes to stabilize Treg-mediated immune homeostasis
Through their functional diversification, CD4+ T cells play key roles in both driving and constraini...
GSE58645: RNA sequencing of mouse littermate wild-type and Shh null E10.5 forelimbs [Illumina]
We wanted to identify differentially expressed genes in wild-type and Shh null E10.5 mouse forelimbs...
GSE48138: Expression and regulation of lincRNAs during T cell development and differentiation
Although lincRNAs are implicated in regulating gene expression in various tissues, little is known a...
GSE53258: The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB)
We report the use of RNAseq to determine the role of the TFEB transcription factor in all-trans reti...
GSE52801: Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance
Recent studies have reported that competitive endogenous RNAs (ceRNAs) can act as sponges for a miRN...
GSE53259: Retinoid induced differentiation of NB4 APL leukemic cells
We report the use of RNAseq to determine genomewide transcriptional changes induced by all-trans ret...