PLX041085

Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency (GSE80972)

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project Understanding the SRF-Myocardin transcriptional switch to develop strategies for the diagnosis and treatment of diseases associated with SRF-Myocardin (Miano lab)

Our results suggest that the expression of VSMC contractile proteins induced by G6PD inhibition occurs via PKG1-dependent and independent pathways SOURCE: Joseph Miano (joseph_miano@URMC.rochester.edu) - Miano Lab University of Rochster

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