PLX053966

GSE99888: Singlecell transcriptomic analysis of mouse CA1 inhibitory neurons

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We studied the transcriptomes of mouse CA1 inhibitory cells. Novel clustering methods identified all 23 previously described CA1 inhibitory types, while also suggesting 6 new inhibitory classes. Latentfactor analysis revealed a common continuum of expression of many genes within and between classes, which we hypothesized correlates with a continuum from fasterspiking cells that proximally target pyramidal cells, to slower active cells targeting pyramidal distal dendrites or interneurons. SOURCE: Sten LinnarssonMolecular Neurobiology Karolinska Institutet

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