PLX323215

GSE99076: Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic metaphase with defects in spindle assembly checkpoint

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

To elucidate the molecular bases for the infertile phenotype of Zmym3 KO mice at the mRNA expression level, we carried out RNA sequencing (RNA-seq) analysis on cultured spermatogonial stem cells (SSCs), c-KIT+ pre-meiotic cells induced from SSCs and spermatocytes directly isolated from adult mouse testes. SOURCE: Chunsheng Han (hancs@ioz.ac.cn) - State Key Laboratory of Reproductive Biology Chinese Academy of Sciences

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