PLX319786

GSE98622: Transcriptome profile of a murine renal bilateral ischemia reperfusion model 2 hours to 12 months post injury

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Acute kidney injury (AKI) is associated with an increased risk of chronic kidney disease (CKD). To extend our understanding of renal repair, and its limits, we performed a detailed molecular characterization of a murine ischemia reperfusion injury (IRI) model for 12 months post injury. RNA-seq analysis highlights a cascade of temporal specific gene expression patterns related to tubular injury/repair, fibrosis, innate and adaptive immunity. SOURCE: Jing Liu (jing.liu@med.usc.edu) - Andy McMahon lab University of Southern California

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