PLX208503

GSE98101: Spatial-temporal epigenetic landscape of mouse gastrula

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Regionalized lineage progenitor cells emerged from the onset of gastrulation would facilitate mouse embryonic patterning and build a blueprint for future development. However, the molecular mechanism especially the epigentic mechanism underlying the formation and development of lineage restricted cells has not been fully unveiled. Here,we present a comprehensive landscape of H3K4me3, H3K4me1, H3K9ac, H3K27ac, H3K27me3 and DNA methylation pattern in mouse embryo from pre-streak stage to late-streak stage, and fully analyze the epigenetic mechansim driving the embryonic patterning of mouse gastrula SOURCE: Naihe Jing (njing@sibcb.ac.cn) - shanghai institute of biochemistry and cell biology

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