PLX110874

GSE97126: Constitutive Activation of HH-GLI Signaling in the Metanephric Mesenchyme causes Ureteropelvic Junction Obstruction during Mammalian Embryogenesis

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

This study explores the underlying pathogenic mechanisms of congenital intrinsic obstruction of the ureteropelvic junction. A hedgehog-dependent mechanism underlying mammalin intrinsic ureteropelvic obstruction is defined. SOURCE: Steve Potter (steve.potter@cchmc.org) - Cincinnati Children's Hospital Medical Center

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