PLX314549

GSE95771: AG221 and Ruxolitinib Treatment Effects on LSKs in IDH2-R140Q JAK2-V617F Transplant Recipients

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Transplant recipients of IDH2-R140Q JAK2-V617F expressing bone marrow were treated with AG221 and ruxolitinib monotherapy, combined therapy, or vehicle. LSKs were sorted from terminal samples and sequenced with three WT controls. SOURCE: Barbara Spitzer (spitzerb@mskcc.org) - Levine Lab Memorial Sloan Kettering Cancer Center

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