PLX310510

GSE93870: Zika virus infection reprograms global transcription of host cells to allow sustained infection

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and GuillainBarre syndrome. There are currently no targeted therapies for ZIKV infection. To identify novel antiviral targets and to elucidate the mechanisms by which ZIKV exploits the host cell machinery to support sustained replication, we analyzed the transcriptomic landscape of human microglia, fibroblast, embryonic kidney, and monocyte-derived macrophage cell lines before and after ZIKV infection. SOURCE: Tariq Rana (trana@ucsd.edu) - University of California, San Diego

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