PLX310311

GSE93807: Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

We examined the transcriptional changes modulated by ESR2 agonist liquiritigenin by perfroming global transcriptome analysis. ES2 cells were treated with either vehicle or liquiritigenin for 24 h and the isolated RNA was utilized for RNA-seq analysis. Our results demonstrated that liquiritigenin modulated several genes that are involved in NF-kB signaling, inflammation, NRF2 mediated oxidative stress response, and MMP signaling. SOURCE: Hung-I,Harry,Chen University of Texas Health Science Center at San Antonio

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