PLX307904

GSE93156: Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3K Inhibitor Idelalisib

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

RNAseq profile of TMD8 cell lines resistant to Idelalisib treatment. Idelalisib resistant TMD8 cells were generated by continuous passage in the presence of 1 M idelalisib for 8 weeks until stable resistance to idelalisib was established. Parallel cultures were grown in the presence of 0.1% DMSO as passage-matched, drug-sensitive control lines. Sensitive and resistant TMD8 cells were clonally isolated through two rounds of single cell limiting dilution SOURCE: Li Li (li.li@gilead.com) - Gilead Sciences

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