PLX154246

GSE92721: Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Analysis of transcriptome of prostate tissue from the anterior lobe or tumor from 9, 12, 13, 14, and 16 months old mouse; Prostate tissue or tumor from 9 month old Nkx3.1CreERT2/+ mice, 14 month old Nkx3.1CreERT2/+;Ptenflox/flox mice (intact, treated with vehicle), 16 month old Nkx3.1CreERT2/+;Ptenflox/flox mice (castrated, treated with vehicle or abiraterone), 12 month old Nkx3.1CreERT2/+;Ptenflox/flox;P53flox/flox mice(intact, treated with vehicle), 13 month old Nkx3.1CreERT2/+;Ptenflox/flox;P53flox/flox mice (castrated, treated with vehicle or abiraterone) was harvested, and snap frozen for subsequent molecular analysis SOURCE: Antonina Mitrofanova (mitrofanova.antonina@hotmail.com) - Rutgers University

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