PLX291821

GSE84953: Cnot3-dependent mRNA deadenylation safeguards the pluripotent state

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Poly(A)-tail length and mRNA deadenylation play important roles in post-transcriptional gene regulation. Here, we report the regulation of mRNA expression, half-life, and polysome association in mouse embryonic stem cells by the Cnot3 subunit in the Ccr4-Not mRNA deadenylase complex. SOURCE: Guang Hu (guang.hu@nih.gov) - Stem Cell Biology Group NIH/NIEHS

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