PLX057195

GSE78845: Single cell transcriptome analysis of mouse thoracic sympathetic ganglia

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

We explore the heterogeneity of mouse thoracic ganglia demonstrating the presence of an unexpected variety of cell-types and identify specialized populations of nipple- and pilo-erector muscle neurons. These neurons extend axonal projections and are born amongst other neurons during embryogenesis, but remain unspecialized until target organogenesis occurs postnatally. Target innervation and cell-type specification is coordinated by an intricate acquisition of unique combinations of growth factor receptors and the initiation of expression of concomitant ligands by the nascent erector muscles. SOURCE: Sten LinnarssonMolecular Neurobiology Karolinska Institutet

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