PLX278871

GSE76419: Dino-dependent gene expression signature in MEFs

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Genetically modified Dino mice were generated with loxP sites flanking the mouse Dino gene. We set out to identify the set of genes regulated by Dino in DNA damaged mouse embryonic fibroblasts using 3' sequencing. Early passage Dino+/+ or Dino loxP/loxP MEFs were treated with 0.2ug/mL doxorubicin prior to addition of Trizol and RNA isolation. SOURCE: Adam Schmitt (amschmit@stanford.edu) - Howard Y. Chang Stanford University

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