PLX267672

GSE74383: Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway

• Organsim human
• Type RNASEQ
• Target gene
• Project ARCHS4

RNA-Seq profiling of estrogen-receptor-positive MCF-7 cell lines with different perturbations of non-canonical WNT signaling .; The MCF-7 cells were either transfected with an empty vector (pcDNA) or with a ROR2 overexpression construct, in parallel with or without stimulation with recombinant WNT5A. The objective was to find expression-responsive targets of these perturbations as potential drivers of increased cell invasiveness. SOURCE: Tim Beissbarth (tim.beissbarth@ams.med.uni-goettingen.de) - University Medical Center Göttingen