PLX147862

GSE69276: Notch1 dose modulates endothelial gene expression

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Purpose: To use RNA-Seq analysis of endothelial cell in various Notch1 alllels in order to determine transcrptional differencesas a consequence of Notch dose.; Methods: Using a FACS sorting we generated high-throughput RNA-SEQ data of endothelials in various Notch1 alleles during development; Results: Notch1 dose can alter gene expression in a subset of endothelial genes SOURCE: Raphael Kopan Cincinnati Children's Hospital

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