PLX239775

GSE65422: Gene expression profiling and mutation analysis of B cell lymphomas arising in mice expressing NIK and BCL6 transgenes

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

In this study, by RNA sequencing we generated the gene expression profile (GEP) of each mouse lymphoma. By comparing the GEP of a lymphoma to that of normal B cells at physiological differentiation stages, we classified the lymphomas to either ABC- or GCB-type of DLBCL. Analysis of RNA sequencing data also led to identification of various mutations in these lymphomas. SOURCE: Baochun Zhang (Baochun_Zhang@dfci.harvard.edu) - Baochun Zhang Dana-Farber Cancer Institute

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