PLX205257

GSE61425: The miR-155/PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation [RNA-Seq]

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

miR-155 inhibits PU.1 expression, leading to the initiation of the initiation of plasma cell differentiation pathway. Additional PU.1 targets include a network of genes whose products are involved in adhesion, with direct links to B:T interactions. SOURCE: Simon,Richard,Andrews (simon.andrews@babraham.ac.uk) - Bioinformatics The Babraham Institute

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