PLX176730

GSE60065: Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Analysis of lin-CD34+CD45+ (iCD34+) cell population from two normal bone marrow-derived (BM1K and BM9) iPSCs and two CML (CML15 and CML17) iPSCs . CML iCD34+ cells have characteristics similar to primary CML leukemia stem cell in patients. Results provide insight into molecular profile characterized CML iCD34 and mechanism of its maintenance and drug resistance. SOURCE: Scott Swanson (SSWANSON@MORGRIDGEINSTITUTE.ORG) - Thomson Morgridge Institute for Research

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