PLX171166

GSE59463: Polycomb PRC2 antagonizes de novo DNA methylation at the maternal Gtl2-Rian-Mirg locus [Next-Gen Sequence Data]

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Wild-type mouse embryonic stem cells are compared with mutants for components of PRC2 including Ezh2-/-, Eed-/-, and Jarid2-/- cells. Chromatin modifications, Gene expression, Pol-II, small-RNA sequencing, and DNA methylation are compared for both cell types. SOURCE: David Hendrix (dhendrix@csail.mit.edu) - MIT CSAIL

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