PLX007903

GSE35350: Combined miRNA and mRNA Sequencing Identifies Protective Transcriptional Signature of Enhanced PI3Kalpha Signaling in Cardiac Hypertrophy

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

A molecular and bioinformatic pipeline permitting comprehensive analysis and quantification of myocardial miRNA and mRNA expression with next-generation sequencing was developed and the impact of enhanced PI3Kalpha signaling on the myocardial transcriptome signature of pressure overload-induced pathological hypertrophy was explored. SOURCE: Kai-Chien YangNerbonne Washington University in St Louis

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