PLX174096

GSE157433: RNA-seq of Runx3 cKO SFZ/DZ chondrocytes.

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Purpose: To demonstrate Runx3's association with organizing the extracellular matrix in SFZ/DZ chondrocytes.; Method: RNA samples were collected from SFZ/DZ chondrocytes of 5-day-old Col2a1-Cre;Runx3fl/fl and Runx3fl/fl mice.; Results: 18 genes were up- or down-regulated by more than 2-fold in the Runx3 knockout in SFZ.; Conclusions: However, genes organizing the extracellular matrix were down-regulated in Runx3 cKO DZ chondrocytes. SOURCE: Kosei Nagata (knagata-tky@umin.ac.jp) - Sensory and Motor System Medicine the University of Tokyo

View on GEO View in Pluto

Key Features

Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.

Learn More

14K+ Published Experiments

Access an extensive range of curated bioinformatics data sets, including genomic, transcriptomic, and proteomic data.

Easy Data Import

Request imports from GEO or TCGA directly within Pluto Bio. Seamlessly integrate external data sets into your workflow.

Advanced Search Capabilities

Utilize powerful search tools to quickly find the data sets relevant to your research. Filter by type, disease, gene, and more.

Analyze and visualize data for this experiment

Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.

Read about post-pipeline analysis

View QC data and experiment metadata

View quality control data and experiment metadata for this experiment.

Request import of other GEO data

Request imports from GEO or TCGA directly within Pluto Bio.

Chat with our Scientific Insights team