PLX313036

GSE156308: exosomal ELNAT1 promotes lymphatic metastasis of bladder cancer

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

The crosstalk between tumor cells and LECs triggers the LN metastasis in bladder cancer (BCa), but the underlying mechanisms are not completely understood. Previously, we identified that BCa-secreted extracellular vesicles (EVs)-packaged lncRNAs mediated the communication with LECs and promoted LN metastasis. To evaluate whether EV-packaged lncRNAs triggered the LN metastasis of BCa, next-generation sequencing (NGS) to the global expression profiles of lncRNAs was utilized in the urinary EVs (urinary-EV) of five MIBC patients and five healthy volunteers. SOURCE: Yuming Luo Sun yat-sen Memorial Hospital

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