PLX090356

GSE154172: Heat shock protein gp96 induces Foxp3 expression in Regulatory T Cells via interaction with TLRs for treatment of Auto-immune Diseases [Foxp3Cre Myd88fl/fl]

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Upregulate and stabilize Foxp3 expression in Treg are essential for manipulating Treg cell function and immune homeostasis. Here, we examined the potential role and mechanism of gp96 protein in regulating FoxP3 transcription and Treg activation in vivo. SOURCE: Songdong Meng (mengsd@im.ac.cn) - nstitute Of Microbiology Chinese Academy of Sciences

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