PLX067276

GSE154026: Forkhead box a2 (FOXA2) impacts uterine decidualization and fetoplacental development

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Forkhead box a2 (FOXA2) is a transcription factor expressed specifically in the glands of the uterus and a critical regulator of uterine gland differentiation, development and function. Here, we tested the hypothesis that FOXA2-regulated genes in the uterine glands impact development of the decidua, placenta and fetus using a littermate study design. On gestational day (GD) 8.5, the anti-mesometrial and mesometrial RNA was sequenced bewteen wild-type and cKO mice. The anti-mesometrial and mesometrial decidua transcriptome was noticeably altered in FOXA2 cKO mice. SOURCE: Thomas Spencer (spencerte@missouri.edu) - ASRC 158 University of Missouri

View on GEO View in Pluto

Key Features

Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.

Learn More

14K+ Published Experiments

Access an extensive range of curated bioinformatics data sets, including genomic, transcriptomic, and proteomic data.

Easy Data Import

Request imports from GEO or TCGA directly within Pluto Bio. Seamlessly integrate external data sets into your workflow.

Advanced Search Capabilities

Utilize powerful search tools to quickly find the data sets relevant to your research. Filter by type, disease, gene, and more.

Analyze and visualize data for this experiment

Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.

Read about post-pipeline analysis

View QC data and experiment metadata

View quality control data and experiment metadata for this experiment.

Request import of other GEO data

Request imports from GEO or TCGA directly within Pluto Bio.

Chat with our Scientific Insights team