PLX279085
GSE150061: The transcriptional profile of neutrophils in different organs during pancreatic cancer
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
It was previously demonstrated that myeloid cells assume a distinct transcriptional profile when infiltrating the brain during chronic inflammation. We demonstrated that neutrophils infiltrate the brain during pancreatic cancer. To determine if the transcriptional profile of brain-infiltrating neutrophils is distinct from those infiltrating other organs, we compared the gene signatures of brain-infiltrating neutrophils, circulating neutrophils, liver-infiltrating neutrophils, and tumor-infiltrating neutrophils to that of circulating neutrophils from healthy mice. SOURCE: Kevin Burfeind (burfeind@ohsu.edu) - Oregon Health & Science University
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