PLX159942

GSE147327: Single-cell RNA sequencing of wildtype and miR-146a deficient T cells from mice treated with anti-PD-1 therapy

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We observed increased severity of immune related adverse events (irAEs) to anti-PD-1 therapy as well as enhanced T cell effector function in miR-146a deficient mice compared to wildtype (WT) mice. The aim of this experiment was to analyze differences in gene expression between WT and miR-146a deficient T cells at the single cell level. SOURCE: Natalie Köhler University Freiburg Medical Center

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