PLX279515

GSE144370: PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (RNA-seq)

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tumor maintenance because depletion of PAF1 resulted in significantly less tumor burden and reduction in CSC populations. SOURCE: Saswati Karmakar (saswati.karmakar@unmc.edu) - UNMC

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