PLX015006

GSE142535: Therapeutic IDOL reduction ameliorates amyloidosis and improves cognitive function in APP/PS1 mice

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

An antisense oligonucleotide (ASO) against E3 ubiquitin ligase IDOL in the brain significantly decreased A pathology, and improved spatial learning and memory in APP/PS1 mice. SOURCE: Russell Littman (rlittman16@g.ucla.edu) - Yang Lab UCLA

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