PLX133684
GSE141031: Smooth muscle cell reprogramming in aortic aneurysms [scRNA-Seq]
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
Smooth muscle cell TGF signaling is one of the primary drivers of smooth muscle cell maturation. Inhibition of smooth muscle cell TGF signaling in hyperlipidemic mice induces vessel wall inflammation and vessel wall dilation/dissection and leads aortic aneurysm. We performed scRNAseq method to examine smooth muscle cell gene expression profile using Apoe and SMC specific TGFbR2 KO in Apoe background mice. SOURCE: Michael Simons (michael.simons@yale.edu) - Yale Cardiovascular Research Center Yale University
View on GEOView in PlutoKey Features
Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.
Learn MoreAnalyze and visualize data for this experiment
Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.
Read about post-pipeline analysisView QC data and experiment metadata
View quality control data and experiment metadata for this experiment.
Request import of other GEO data
Request imports from GEO or TCGA directly within Pluto Bio.
Chat with our Scientific Insights team