PLX021407

GSE140468: scRNA sequencing of total CD4+ T cells in spinal cord of EAE mice and SILP of SFB-colonized mice

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

There are two aims in this study (1) To figure out the pathogenic sub-populations of CD4+ T cells in the spinal cord of EAE model; and (2) by comparing the gene expression profile of pathogenic Th17 cells in EAE model to that of the non-pathogenic Th17 cells induced by SFB in SILP, to identify genes candidates that are potentially selectively essential to pathogenic ones. SOURCE: Dan Littman New York University School of Medicine

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