PLX260931

GSE138889: Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We analyzed small RNA sequencing data from CD5+/CD19+ B cells of a cohort of indolent and aggressive CLL patients compared with CD19+ B-cells of healthy donors.; We identified tsRNA signatures in indolent and aggressive CLL vs. normal B-cells; we also found a drastic dysregulation of the expression of mature tRFs in CLL. SOURCE: Carlo,Maria,Croce (carlo.croce@osumc.edu) - 1082 Biomedical Research Tower The Ohio State University

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