PLX146548

GSE138485: Retrospective gene expression analysis of human RNA samples from Hepatocellular Carcinoma in relation with survival

• Organsim human
• Type RNASEQ
• Target gene
• Project ARCHS4

The aim of this study is to identify by Next Generation Sequencing - RNA-seq profiling a molecular signature of Hepatocellular Carcinoma samples that correlates with survival. The samples were retrospectively derived from hepatocellular carcinoma tissue as well as non-tumor tissue from the livers of the same patients. The bioinformatical analysis of 23 pairs RNA-seq datasets were obtained from human RNAs on Illumina Hiseq-PE150. Due to the lack of biological sample duplication, this datasets were used hisat2 2.1.0 and gfold v1.1.4 for expression analysis to identify differences in gene expression between tumors and adjacent tissues. (including up- and down-regulation). SOURCE: Hechen Huang (21618114@zju.edu.cn) - NHFPC Key Laboratory of Combined Multi-organ Transplantation First Affiliated Hospital, School of Medicine, Zhejiang University