PLX279007

GSE136655: NON-CELL AUTONOMOUS FUNCTIONS OF SPHINGOSINE KINASE 2 AND TP53 IN ANTI-TUMOR IMMUNITY

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We compared the global transcriptomes of wild type and SphK2 null fibroblasts by RNA-seq as a first step toward understanding the mechanism by which deletion or inhibition of SphK2 and elevation of p53 acts in a non-cell autonomous manner to create a hostile, anti-tumor microenvironment. SOURCE: Mikhail Dozmorov (mdozmorov@vcu.edu) - Virginia Commonwealth University

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