PLX174584

GSE136216: EGR1 as gatekeeper of inflammatory enhancers during immune cell development

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

We investigated the function of EGR1 in macrophage differentiation and activation. We generated EGR1 CHIP-seq and CUT-and-RUN data during GM-CSF induced macrophage differentiation, paired with ATAC-seq. We performed RNA-seq and CHIP-seq for H3K27ac in EGR1-depleted differentiated macrophages. Finally we generated RNA-seq data in activated macrophages with EGR1 overexpression. SOURCE: Marco Trizzino (marco.trizzino83@gmail.com) - The Wistar Institute

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