PLX141021

GSE133898: Stem cells utilize m6A-mediated decay via YTHDF2 to regulate neural differentiation and promote pluripotency

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

The m6A methylation pathway has previously been shown to influence pluripotency. YTHDF2 is an RNA binding protein that interacts with m6A-modified RNAs to facilitate their degradation. We sought to identify the cohort of RNAs targeted by YTHDF2 in human induced pluripotent stem cells (iPSC). SOURCE: Carol,J,Wilusz (cwilusz@colostate.edu) - Carol Wilusz Lab Colorado State University

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