PLX095826

GSE133677: LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-B/p50 and SLUG

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

We provide evidence that NOAT113026 inhibits renal cancer proliferative and mobility potential by blocking NF-B/p50 and SLUG expression, which consequently inhibiting the production of oncogenic chemokines and metastasis-promoting genes. Our findings manifest that NOAT113026 may become a critical and feasible target for RCC treatment because of its anti-proliferative and anti-metastatic properties and emerge as an important biomarker for the detection of overall survival and disease-free survival. SOURCE: yan pu (15276563356@163.com) - Institute of Cancer Research

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