PLX069346
GSE133566: Shp-deletion induces dissociation of steatosis and inflammation in NASH
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
Two months-old Shp flox/flox male mice were injected with either AAV8 expressing Cre recombinase driven by the thyroxine-binding globulin (Tbg) promoter (AAV8-Tbg-Cre) or control AAV8 (AAV8-Tbg-null) and fed chow or a diet enriched in high fat, cholesterol, and fructose (Research diet D09100301: 40 kcal% fat, 2% cholesterol, 20 kcal% fructose, hereafter referred to as HFCF diet) for 3 months. Liver RNA was isolated and submitted to RNA-seq. SOURCE: Yuxia Zhang (lzhang5@kumc.edu) - University of Kansas Medical Center
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