PLX080268

GSE132340: Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

Comparison of the TP53 wild-type myeloma cell line AMO1 with the CRISPR/Cas9 engineered AMO1 cell line named UMC901. UMC901 harbors bi-allelic alterations to TP53: TP53 del/mut. Analysis of impact of TP53 alterations on gene transcription and identification of affected pathways by transcriptome-wide differential gene expression analysis. SOURCE: Tobias Heckel (ht-seq.sysmed@uni-wuerzburg.de) - Raum D15.02.045 University of Wuerzburg

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